Heart transplantation from donors with left ventricular ejection fraction under 40

Heart transplantation (HTx) remains the treatment of choice for patients with end-stage advanced heart failure. In 2016 the Schumakov National Medical Research Center commenced performing HTx from donors with abnormal left ventricular systolic function (LVEF 60%). The use of dysfunctional donor hear...

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Bibliographic Details
Published in:Clinical transplantation 2021-05, p.e14341
Main Authors: Poptsov, Vitalii, Khatutskiy, Valery, Skokova, Anastasiia, Krasivskyi, Ihor, Sabashnikov, Anton, Merkle-Storms, Julia, Spirina, Ekaterina
Format: Article
Language:English
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Summary:Heart transplantation (HTx) remains the treatment of choice for patients with end-stage advanced heart failure. In 2016 the Schumakov National Medical Research Center commenced performing HTx from donors with abnormal left ventricular systolic function (LVEF 60%). The use of dysfunctional donor hearts with impaired LV systolic function may be a realistic approach for expanding the donor pool. However, organs from such donors should be used for recipient cohorts requiring an urgent HTx, particularly for those with pretransplant mechanical circulatory support allowing for hemodynamic support in cases of early graft dysfunction in the post-transplant period.
ISSN:1399-0012