Ambulatory Intrapleural Fibrinolytic Therapy in Highly Viscous Recurrent Malignant Pleural Effusion

Malignant pleural effusion (MPE) is common in lung cancer. We report a case of highly viscous recurrent MPE associated with lung cancer. The viscosity prohibited gravity-dependent drainage initially with a 6-Fr aspiration catheter and subsequently with a 12-Fr intercostal drain. The effusion was eve...

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Bibliographic Details
Published in:Case reports in oncology 2021-01, Vol.14 (1), p.466-469
Main Authors: Foo, Chuan Tai, Herre, Jurgen
Format: Article
Language:English
Subjects:
Case Report
Case reports
Catheters
Drainage
Dyspnea
Enzymes
Hyaluronic acid
Immunotherapy
Infections
intrapleural fibrinolytic therapy
Lung cancer
malignant pleural effusion
Pleural effusion
Thoracentesis
Ultrasonic imaging
Viscosity
viscous pleural effusion
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Summary:Malignant pleural effusion (MPE) is common in lung cancer. We report a case of highly viscous recurrent MPE associated with lung cancer. The viscosity prohibited gravity-dependent drainage initially with a 6-Fr aspiration catheter and subsequently with a 12-Fr intercostal drain. The effusion was eventually evacuated after a single dose of intrapleural fibrinolytic therapy. This process was repeated a total of 13 times over a 12-month period in an ambulatory setting. No bleeding complications were observed. This case highlights the feasibility and safety of repeated intrapleural fibrinolysis in the management of highly viscous recurrent MPE in an ambulatory setting.
ISSN:1662-6575
1662-6575
DOI:10.1159/000515077