Successful treatment of cutaneous leishmaniasis with simulated daylight photodynamic therapy

A 5-year-old Syrian boy , presented with a complex cutaneous leishmaniasis (CL) of the right ankle caused by Leishmania (L.) tropica. The patient received photodynamic therapy (PDT; 6 cycles with application of 5‑aminolevulinic acid and foil occlusion for 3 h). Due to pain during exposure to red lig...

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Bibliographic Details
Published in:Hautarzt 2022-05, Vol.73 (5), p.376
Main Authors: Hobelsberger, Sarah, Krauß, Marie-Paloma, Bogdan, Christian, Aschoff, Roland
Format: Article
Language:ger
Subjects:
Aminolevulinic Acid - therapeutic use
Child, Preschool
Humans
Leishmania tropica
Leishmaniasis, Cutaneous - diagnosis
Leishmaniasis, Cutaneous - drug therapy
Male
Pain
Photochemotherapy
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Description
Summary:A 5-year-old Syrian boy , presented with a complex cutaneous leishmaniasis (CL) of the right ankle caused by Leishmania (L.) tropica. The patient received photodynamic therapy (PDT; 6 cycles with application of 5‑aminolevulinic acid and foil occlusion for 3 h). Due to pain during exposure to red light, exposure was continued with simulated daylight (sDL-PDT). The lesion healed with an atrophic scar. Due to fewer side effects and less pain, sDL-PDT seems to be a good therapeutic strategy for CL caused by L. tropica.
ISSN:1432-1173
DOI:10.1007/s00105-021-04852-y