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Transarterial embolization with hepatectomy for ruptured hepatocellular carcinoma: a meta-analysis
To compare the clinical effectiveness between transarterial embolization (TAE) with staged hepatectomy (SH) and emergency hepatectomy (EH) for ruptured hepatocellular carcinoma (HCC). Pubmed, Embase, and Cochrane Library databases were screened for eligible publications from the inception of the dat...
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Published in: | Minimally invasive therapy and allied technologies 2022-06, Vol.31 (5), p.676-683 |
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container_title | Minimally invasive therapy and allied technologies |
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creator | Zhang, Feng-Qin Li, Lin Huang, Ping-Chao Fu, Yu-Fei Xu, Qing-Song |
description | To compare the clinical effectiveness between transarterial embolization (TAE) with staged hepatectomy (SH) and emergency hepatectomy (EH) for ruptured hepatocellular carcinoma (HCC).
Pubmed, Embase, and Cochrane Library databases were screened for eligible publications from the inception of the databases till February 2021.
This meta-analysis included seven studies comprising 162 patients who underwent TAE with SH and 266 patients who underwent EH. The pooled intraoperative blood loss was less in the TAE with SH cohort, as compared to the EH cohort without significant difference (p = .20). The pooled blood transfer rate (p |
doi_str_mv | 10.1080/13645706.2021.1986724 |
format | article |
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Pubmed, Embase, and Cochrane Library databases were screened for eligible publications from the inception of the databases till February 2021.
This meta-analysis included seven studies comprising 162 patients who underwent TAE with SH and 266 patients who underwent EH. The pooled intraoperative blood loss was less in the TAE with SH cohort, as compared to the EH cohort without significant difference (p = .20). The pooled blood transfer rate (p<.00001), blood transfer volume (p = .002), and 30-day patient death (p = .04) were all markedly reduced in the TAE with SH cohort versus the EH cohort. No significant differences in surgery duration (p = .27), hospital stay period (p = .81), complication rate (p = 0.92), disease-free survival (DFS) (p = .79), and overall survival (OS) (p = 0.28) were found between the two groups.
Compared with EH for ruptured HCC, TAE with SH could effectively decrease intraoperative blood loss and 30-day mortality. However, the long-term DFS and OS might not be beneficial to preoperative TAE.</description><identifier>ISSN: 1364-5706</identifier><identifier>EISSN: 1365-2931</identifier><identifier>DOI: 10.1080/13645706.2021.1986724</identifier><identifier>PMID: 34634985</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Hepatectomy ; hepatocellular carcinoma ; rupture ; transarterial embolization</subject><ispartof>Minimally invasive therapy and allied technologies, 2022-06, Vol.31 (5), p.676-683</ispartof><rights>2021 Society of Medical Innovation and Technology 2021</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c366t-f83db7b58ff493272f91d1c2b5477f0f52b6f1a037fb7f5002ade95b16077a9d3</citedby><cites>FETCH-LOGICAL-c366t-f83db7b58ff493272f91d1c2b5477f0f52b6f1a037fb7f5002ade95b16077a9d3</cites><orcidid>0000-0002-6772-6557</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34634985$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Feng-Qin</creatorcontrib><creatorcontrib>Li, Lin</creatorcontrib><creatorcontrib>Huang, Ping-Chao</creatorcontrib><creatorcontrib>Fu, Yu-Fei</creatorcontrib><creatorcontrib>Xu, Qing-Song</creatorcontrib><title>Transarterial embolization with hepatectomy for ruptured hepatocellular carcinoma: a meta-analysis</title><title>Minimally invasive therapy and allied technologies</title><addtitle>Minim Invasive Ther Allied Technol</addtitle><description>To compare the clinical effectiveness between transarterial embolization (TAE) with staged hepatectomy (SH) and emergency hepatectomy (EH) for ruptured hepatocellular carcinoma (HCC).
Pubmed, Embase, and Cochrane Library databases were screened for eligible publications from the inception of the databases till February 2021.
This meta-analysis included seven studies comprising 162 patients who underwent TAE with SH and 266 patients who underwent EH. The pooled intraoperative blood loss was less in the TAE with SH cohort, as compared to the EH cohort without significant difference (p = .20). The pooled blood transfer rate (p<.00001), blood transfer volume (p = .002), and 30-day patient death (p = .04) were all markedly reduced in the TAE with SH cohort versus the EH cohort. No significant differences in surgery duration (p = .27), hospital stay period (p = .81), complication rate (p = 0.92), disease-free survival (DFS) (p = .79), and overall survival (OS) (p = 0.28) were found between the two groups.
Compared with EH for ruptured HCC, TAE with SH could effectively decrease intraoperative blood loss and 30-day mortality. However, the long-term DFS and OS might not be beneficial to preoperative TAE.</description><subject>Hepatectomy</subject><subject>hepatocellular carcinoma</subject><subject>rupture</subject><subject>transarterial embolization</subject><issn>1364-5706</issn><issn>1365-2931</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp9kEtPwzAMgCME4jH4CaAeuXTk0TQNJxDiJSFxGefIaRMRlDYjSYXGr6djG0dOjuzPsf0hdE7wnOAGXxFWV1zgek4xJXMim1rQag8dT3leUsnI_u-7KtfQETpJ6QNPJGfNITpiVc0q2fBjpBcRhgQxm-jAF6bXwbtvyC4MxZfL78W7WUI2bQ79qrAhFnFc5jGablMIrfF-9BCLFmLrhtDDdQFFbzKUMIBfJZdO0YEFn8zZNs7Q28P94u6pfHl9fL67fSlbVte5tA3rtNC8sbaSjApqJelISzWvhLDYcqprSwAzYbWwfDoGOiO5JjUWAmTHZuhy8-8yhs_RpKx6l9b7wWDCmBTlDaGNrCSZUL5B2xhSisaqZXQ9xJUiWK31qp1etdartnqnvovtiFH3pvvr2vmcgJsN4IZJVg9fIfpOZVj5EO1kunVJsf9n_ABAroub</recordid><startdate>202206</startdate><enddate>202206</enddate><creator>Zhang, Feng-Qin</creator><creator>Li, Lin</creator><creator>Huang, Ping-Chao</creator><creator>Fu, Yu-Fei</creator><creator>Xu, Qing-Song</creator><general>Taylor & Francis</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6772-6557</orcidid></search><sort><creationdate>202206</creationdate><title>Transarterial embolization with hepatectomy for ruptured hepatocellular carcinoma: a meta-analysis</title><author>Zhang, Feng-Qin ; Li, Lin ; Huang, Ping-Chao ; Fu, Yu-Fei ; Xu, Qing-Song</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c366t-f83db7b58ff493272f91d1c2b5477f0f52b6f1a037fb7f5002ade95b16077a9d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Hepatectomy</topic><topic>hepatocellular carcinoma</topic><topic>rupture</topic><topic>transarterial embolization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Feng-Qin</creatorcontrib><creatorcontrib>Li, Lin</creatorcontrib><creatorcontrib>Huang, Ping-Chao</creatorcontrib><creatorcontrib>Fu, Yu-Fei</creatorcontrib><creatorcontrib>Xu, Qing-Song</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Minimally invasive therapy and allied technologies</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Feng-Qin</au><au>Li, Lin</au><au>Huang, Ping-Chao</au><au>Fu, Yu-Fei</au><au>Xu, Qing-Song</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transarterial embolization with hepatectomy for ruptured hepatocellular carcinoma: a meta-analysis</atitle><jtitle>Minimally invasive therapy and allied technologies</jtitle><addtitle>Minim Invasive Ther Allied Technol</addtitle><date>2022-06</date><risdate>2022</risdate><volume>31</volume><issue>5</issue><spage>676</spage><epage>683</epage><pages>676-683</pages><issn>1364-5706</issn><eissn>1365-2931</eissn><abstract>To compare the clinical effectiveness between transarterial embolization (TAE) with staged hepatectomy (SH) and emergency hepatectomy (EH) for ruptured hepatocellular carcinoma (HCC).
Pubmed, Embase, and Cochrane Library databases were screened for eligible publications from the inception of the databases till February 2021.
This meta-analysis included seven studies comprising 162 patients who underwent TAE with SH and 266 patients who underwent EH. The pooled intraoperative blood loss was less in the TAE with SH cohort, as compared to the EH cohort without significant difference (p = .20). The pooled blood transfer rate (p<.00001), blood transfer volume (p = .002), and 30-day patient death (p = .04) were all markedly reduced in the TAE with SH cohort versus the EH cohort. No significant differences in surgery duration (p = .27), hospital stay period (p = .81), complication rate (p = 0.92), disease-free survival (DFS) (p = .79), and overall survival (OS) (p = 0.28) were found between the two groups.
Compared with EH for ruptured HCC, TAE with SH could effectively decrease intraoperative blood loss and 30-day mortality. However, the long-term DFS and OS might not be beneficial to preoperative TAE.</abstract><cop>England</cop><pub>Taylor & Francis</pub><pmid>34634985</pmid><doi>10.1080/13645706.2021.1986724</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-6772-6557</orcidid></addata></record> |
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language | eng |
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source | Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
subjects | Hepatectomy hepatocellular carcinoma rupture transarterial embolization |
title | Transarterial embolization with hepatectomy for ruptured hepatocellular carcinoma: a meta-analysis |
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