Repeated Intravenous Thrombolysis in Patients with Recurrent Ischemic Stroke in the Vertebrobasilar Territory

Abstract Acute ischemic vertebrobasilar stroke (AIVBS) is usually associated with poor outcome and prognosis and in case of basilar artery occlusion (BAO) with high mortality. Intravenous thrombolysis (IVT), as a standard recanalization therapy of acute ischemic stroke (IS) within first 4.5 h, can b...

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Bibliographic Details
Published in:Case reports in neurology 2021-05, Vol.13 (2), p.510-514
Main Authors: Černík, David, Ospalík, Dušan, Šaňák, Daniel, Cihlář, Filip
Format: Article
Language:English
Subjects:
Anticoagulants
Ataxia
basilar artery occlusion
Blood clots
Case reports
Case Series - General Neurology
Contraindications
Dysarthria
Embolization
eptifibatide
Ischemia
ischemic stroke
Medical prognosis
Paresis
Patients
repeated intravenous thrombolysis
Stroke
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Summary:Abstract Acute ischemic vertebrobasilar stroke (AIVBS) is usually associated with poor outcome and prognosis and in case of basilar artery occlusion (BAO) with high mortality. Intravenous thrombolysis (IVT), as a standard recanalization therapy of acute ischemic stroke (IS) within first 4.5 h, can be administrated beyond this therapeutic time window in case of symptomatic BAO. Repeated IVT is generally contraindicated in case of early recurrent IS, despite a risk of poor outcome or death after recurrent IS. The aim was to present 2 cases of repeated IVT for recurrent AIVBS and discuss specific situations where repeated IVT may be considered. Up to now, repeated IVT has been reported only in recurrent stroke in anterior circulation.
ISSN:1662-680X
1662-680X
DOI:10.1159/000518193