Implementation of the Frequency Scatter Index in Clinical Commercially Available Double-pass Systems

• Published in: Current eye research 2022-03, Vol.47 (3), p.391-398
• Main Authors: Sánchez, Roberto F., García-Guerra, Carlos E., Martínez-Roda, Joan A., de Paul, Aníbal G., Issolio, Luis A., Pujol, Jaume
• Format: Article
• Language: English
• Subjects: Cataract - diagnosis; cataracts; Double-pass system; frequency scatter index; Humans; intraocular scattering; Light; objective scatter index; Retina; Scattering, Radiation; Vision, Ocular
• ISSN: 0271-3683; 1460-2202
• DOI: 10.1080/02713683.2021.2002908

A previous work has reported a methodology to quantify intraocular scattering using a high sensitivity double-pass instrument with a robust index, the frequency scatter index. The purpose of our study was to evaluate an adaptation of the frequency scatter index for use in clinical double-pass systems. A prospective observational study was carried out in a group of patients with nuclear cataracts (n = 52) and in a control group (n = 11) using conventional double-pass systems. The frequency scatter index and the objective scatter index were used to assess the scattering. The Spearman coefficient was calculated to assess the correlation between both indexes, obtained from the double-pass images. Simultaneous measurements were performed with a double-pass and with a Hartmann-Shack wavefront sensor in the control group. The root-mean-square wavefront error and the full width at half maximum of the double-pass image were used to quantify the residual aberrations introduced by the variations in pupil size and retinal eccentricity. Measurement in eyes with different grades of cataracts shows a strong correlation (ρ = 0.929, p