The diagnostic value of systemic immune-inflammation index in diabetic macular oedema

Diabetic macular oedema (DME) is a significant cause of visual impairment and inflammation plays an important role in its pathophysiology. This study evaluates the diagnostic value of systemic immune-inflammation index (SII) in the occurrence of DME in patients with non-proliferative diabetic retino...

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Bibliographic Details
Published in:Clinical and experimental optometry 2022-11, Vol.105 (8), p.831-835
Main Authors: Elbeyli, Ahmet, Kurtul, Bengi Ece, Ozcan, Sait Coskun, Ozarslan Ozcan, Deniz
Format: Article
Language:English
Subjects:
Diabetes
Diabetes mellitus
Diabetic macular oedema
Diabetic retinopathy
Edema
Inflammation
Leukocytes (neutrophilic)
Lymphocytes
Medical diagnosis
Patients
Regression analysis
Retina
Retinopathy
Risk factors
subretinal fluid
systemic immune-inflammation index
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Summary:Diabetic macular oedema (DME) is a significant cause of visual impairment and inflammation plays an important role in its pathophysiology. This study evaluates the diagnostic value of systemic immune-inflammation index (SII) in the occurrence of DME in patients with non-proliferative diabetic retinopathy. In this prospective study, the SII was applied to 150 consecutive patients with non-proliferative diabetic retinopathy. The relationship between the SII and the occurrence of DME was examined. Patients with DME were also divided into two subgroups according to the presence of accompanying sub-retinal fluid. The SII value was calculated as follows: platelet count × (neutrophil/lymphocyte). The risk factors for DME were evaluated using multivariate logistic regression analysis. A receiver operating characteristic (ROC) curve analysis of SII for predicting DME was performed. Patients with DME had significantly higher levels of SII than those without DME (599.7 ± 279.2 and 464. 9 ± 172.2, respectively, p
ISSN:0816-4622
1444-0938
DOI:10.1080/08164622.2021.1994337