Exploring the Potential of Stem Cell-Based Therapy for Aesthetic and Plastic Surgery

Over the last decade, stem cell-associated therapies are widely used because of their potential in self-renewable and multipotent differentiation ability. Stem cells have become more attractive for aesthetic uses and plastic surgery, including scar reduction, breast augmentation, facial contouring,...

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Bibliographic Details
Published in:IEEE reviews in biomedical engineering 2023, Vol.16, p.386-402
Main Authors: Tran, Dang-Khoa, Phuong, Thuy Nguyen Thi, Bui, Nhat-Le, Singh, Vijai, Looi, Qi Hao, Koh, Benson, Zaman, Ungku Mohd Shahrin B Mohd, Foo, Jhi Biau, Wu, Chia-Ching, Show, Pau Loke, Chu, Dinh-Toi
Format: Article
Language:English
Subjects:
Adipose Tissue - transplantation
aesthetic medicine
Aging
Bones
Cell differentiation
Cicatrix
clinical applications
Contouring
Diseases
Esthetics
grafting
Humans
Medical treatment
Plastic surgery
Plastics
Reviews
self-renewable
Skin
Stem Cells
Surgery
Surgery, Plastic
Therapy
Tissue engineering
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Summary:Over the last decade, stem cell-associated therapies are widely used because of their potential in self-renewable and multipotent differentiation ability. Stem cells have become more attractive for aesthetic uses and plastic surgery, including scar reduction, breast augmentation, facial contouring, hand rejuvenation, and anti-aging. The current preclinical and clinical studies of stem cells on aesthetic uses also showed promising outcomes. Adipose-derived stem cells are commonly used for fat grafting that demonstrated scar improvement, anti-aging, skin rejuvenation properties, etc. While stem cell-based products have yet to receive approval from the FDA for aesthetic medicine and plastic surgery. Moving forward, the review on the efficacy and potential of stem cell-based therapy for aesthetic and plastic surgery is limited. In the present review, we discuss the current status and recent advances of using stem cells for aesthetic and plastic surgery. The potential of cell-free therapy and tissue engineering in this field is also highlighted. The clinical applications, advantages, and limitations are also discussed. This review also provides further works that need to be investigated to widely apply stem cells in the clinic, especially in aesthetic and plastic contexts.
ISSN:1937-3333
1941-1189
DOI:10.1109/RBME.2021.3134994