A Rare Cause of Gastric Variceal Bleeding

Abstract A 68-year-old woman with stage III colon cancer status after right hemicolectomy and adjuvant FOLFOX (5-fluorouracil/leucovorin/oxaliplatin) chemotherapy was hospitalized for melena and found to have new-onset esophageal and gastric varices on esophagogastroduodenoscopy. Her workup did not...

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Bibliographic Details
Published in:Case reports in gastroenterology 2021-09, Vol.15 (3), p.1008-1012
Main Authors: Ramos, Yesenia, Gui, Dorina, Chak, Eric
Format: Article
Language:English
Subjects:
Biopsy
Cancer therapies
Case reports
Chemotherapy
Cholangitis
Colorectal cancer
Embolization
Endoscopy
Esophagus
gastric variceal bleed
Hemorrhage
Hyperplasia
Hypertension
Liver diseases
noncirrhotic portal hypertension
obliterative portal venopathy
oxaliplatin
Patients
Single Case
Surveillance
Thrombocytopenia
Thrombosis
Ultrasonic imaging
Veins & arteries
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Summary:Abstract A 68-year-old woman with stage III colon cancer status after right hemicolectomy and adjuvant FOLFOX (5-fluorouracil/leucovorin/oxaliplatin) chemotherapy was hospitalized for melena and found to have new-onset esophageal and gastric varices on esophagogastroduodenoscopy. Her workup did not reveal an underlying liver disease, but her liver biopsy showed noncirrhotic portal hypertension from obliterative portal venopathy (OPV). The development of OPV is likely from her use of oxaliplatin-based chemotherapy.
ISSN:1662-0631
1662-0631
DOI:10.1159/000521126