The antibacterial property of zinc oxide/graphene oxide modified porous polyetheretherketone against S. sanguinis, F. nucleatum and P. gingivalis

About 30% failures of implant are caused by peri-implantitis. Subgingival plaque, consisting of S. sanguinis, F. nucleatum, , is the initiating factor of peri-implantitis. Polyetheretherketone (PEEK) is widely used for the fabrication of implant abutment, healing cap and temporary abutment in dental...

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Bibliographic Details
Published in:Biomedical materials (Bristol) 2022-03, Vol.17 (2), p.25013
Main Authors: Yang, Shihui, Yu, Wanqi, Zhang, Jingjie, Han, Xiao, Wang, Junyan, Sun, Duo, Shi, Ruining, Zhou, Yanmin, Zhang, Haibo, Zhao, Jinghui
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - chemistry
antibacterial
Benzophenones
graphene oxide
Graphite
Ketones - chemistry
PEEK
Polyethylene Glycols - chemistry
Polymers
Porosity
Zinc Oxide
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Summary:About 30% failures of implant are caused by peri-implantitis. Subgingival plaque, consisting of S. sanguinis, F. nucleatum, , is the initiating factor of peri-implantitis. Polyetheretherketone (PEEK) is widely used for the fabrication of implant abutment, healing cap and temporary abutment in dental applications. As a biologically inert material, PEEK has shown poor antibacterial properties. To promote the antibacterial activity of PEEK, we loaded ZnO/GO on sulfonated PEEK. We screened out that when mass ratio of ZnO/GO was 4:1, dip-coating time was 25 min, ZnO/GO modified SPEEK shown the best physical and chemical properties. At the meantime, the ZnO/GO-SPEEK samples possess a good biocompatibility. The ZnO/GO-SPEEK inhibits obviously, and could exert an antibacterial activity to in the early stage, prevents biofilm formation effectively. With the favorable performances, the modification of PEEK with ZnO/GO is promising for preventing peri-implantitis.
ISSN:1748-6041
1748-605X
DOI:10.1088/1748-605X/ac51ba