The association of interleukin-6, interleukin-27, and body roundness index with gestational diabetes mellitus

We aimed to investigate the relationship between GDM and IL-27, IL-6, and body roundness index (BRI), a new anthropometric measurement more sensitive than BMI in identifying obesity and predicting cardiometabolic outcomes. We enrolled 80 patients, 40 pregnant women with GDM and 40 healthy pregnant w...

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Bibliographic Details
Published in:Journal of obstetrics and gynaecology 2022-08, Vol.42 (6), p.1728-1733
Main Authors: Tutar, Dilek, Çintesun, Feyza Nur İncesu, Günenç, Oğuzhan, Çetinkaya, Çiğdem Damla
Format: Article
Language:English
Subjects:
Body mass index
body roundness index
Cytokines
Gestational diabetes
gestational diabetes mellitus
interleukin-27
interleukin-6
Obesity
Pregnancy
Womens health
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Summary:We aimed to investigate the relationship between GDM and IL-27, IL-6, and body roundness index (BRI), a new anthropometric measurement more sensitive than BMI in identifying obesity and predicting cardiometabolic outcomes. We enrolled 80 patients, 40 pregnant women with GDM and 40 healthy pregnant women at midgestation. The women's anthropometric measurements were recorded and serum markers and IL-6, IL-27 were analysed. At the time of delivery maternal, neonatal results were recorded. Women with GDM had significantly higher pregestational, midgestational and prepartum BMI and midgestational BRI; HOMA-IR; HbA1c; and IL-6 values and lower HDL values (p 4.886 pg/mL), and BRI (>6.708) were found as independent risk factors associated with GDM (p 
ISSN:0144-3615
1364-6893
DOI:10.1080/01443615.2022.2036956