Clinical training and validation of the LeukoScope: a low-cost, point-of-care device to perform white blood cell and neutrophil counts

A white blood cell (WBC) count with partial differential is an important clinical laboratory test. However, current methods to perform a WBC count and differential are difficult to use at the point of care or too expensive for use in low-resource settings. To meet this need, we developed the LeukoSc...

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Bibliographic Details
Published in:RSC advances 2019-08, Vol.9 (47), p.27324-27333
Main Authors: Majors, Catherine E, Pawlowski, Michal E, Burke, Daniel C, Tkaczyk, Tomasz S, Rieber, Alyssa, Richards-Kortum, Rebecca
Format: Article
Language:English
Subjects:
Blood
Cartridges
Chemistry
Color imagery
Fluorescence
Laboratories
Laboratory tests
Leukocytes
Low cost
Neutrophils
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Summary:A white blood cell (WBC) count with partial differential is an important clinical laboratory test. However, current methods to perform a WBC count and differential are difficult to use at the point of care or too expensive for use in low-resource settings. To meet this need, we developed the LeukoScope: a low-cost system to measure a WBC and neutrophil count from a single drop of blood at the point of care. The LeukoScope is battery powered and has a sample-to-answer time of
ISSN:2046-2069
2046-2069
DOI:10.1039/c9ra06433h