Cognitive remediation therapy for post-acute persistent cognitive deficits in COVID-19 survivors: A proof-of-concept study

Cognitive impairments figure prominently in COVID-19 survivors. Cognitive remediation therapy (CRT) improves functional outcomes reducing long-term cognitive deficits in several neurological and psychiatric conditions. Our case-control study investigates the efficacy of a CRT programme administered...

Full description

Saved in:
Bibliographic Details
Published in:Neuropsychological rehabilitation 2023-08, Vol.33 (7), p.1207-1224
Main Authors: Palladini, Mariagrazia, Bravi, Beatrice, Colombo, Federica, Caselani, Elisa, Di Pasquasio, Camilla, D'Orsi, Greta, Rovere-Querini, Patrizia, Poletti, Sara, Benedetti, Francesco, Mazza, Mario Gennaro
Format: Article
Language:English
Subjects:
Civil Engineering
Cognitive ability
Cognitive functioning
Cognitive impairment
Cognitive remediation therapy
Coordination
COVID-19
Depression
Efficacy
Engineering Sciences
Executive function
Fluency
Functional impairment
Human health and pathology
Life Sciences
Mental depression
Neurological diseases
Psychiatrics and mental health
Quality of life
Rehabilitation
SARS-CoV-2
Short term memory
Survivor
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cognitive impairments figure prominently in COVID-19 survivors. Cognitive remediation therapy (CRT) improves functional outcomes reducing long-term cognitive deficits in several neurological and psychiatric conditions. Our case-control study investigates the efficacy of a CRT programme administered to COVID-19 survivors in the post-acute phase of the illness. Seventy-three COVID-19 survivors presenting cognitive impairments at one-month follow-up were enrolled. Among them, 15 patients were treated with a two-month CRT programme, and 30 non-treated patients were matched conditional to their baseline cognitive functioning. Cognitive functions were assessed before and after treatment. Depression and quality of life were also evaluated. Mixed model ANOVA revealed a significant effect over time of the CRT programme on global cognitive functioning (F = 4.56, p = 0.039), while no significant effect was observed in the untreated group. We observed a significant effect of the improvement in verbal fluency (χ 2  = 7.20, p = 0.007) and executive functions (χ 2  = 13.63, p 
ISSN:0960-2011
1464-0694
DOI:10.1080/09602011.2022.2075016