Effect of resistance training combined with β-glucan ingestion on bone of ovariectomized mice

This study aimed to evaluate the effects of resistance training (RT) combined with prebiotic β-glucan (BG) ingestion (Saccharomyces cerevisiae) in ovariectomized (OVX) mice. Forty-eight mice were divided into six treatments: SHAM group and five OVX groups treated with saline (SAL), alendronate (ALE)...

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Published in:Climacteric : the journal of the International Menopause Society 2022-12, Vol.25 (6), p.595-602
Main Authors: Galdino-Alves, D. A., Pereira, G. J. de Sá, Bertolini, N. de Oliveira, Ferreira, R. D., Santos, M. de Souza, Barrioni, B. R., Pereira, M. de Magalhães, Andrade, E. F., Bianco-Borges, B. Del, Pereira, L. J.
Format: Article
Language:English
Subjects:
Alendronate - pharmacology
Animals
beta-Glucans - pharmacology
Bone Density
Eating
estrogen
Female
Femur
Humans
Mice
Osteoporosis
Ovariectomy
Resistance Training
Strength training
β-glucan
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Summary:This study aimed to evaluate the effects of resistance training (RT) combined with prebiotic β-glucan (BG) ingestion (Saccharomyces cerevisiae) in ovariectomized (OVX) mice. Forty-eight mice were divided into six treatments: SHAM group and five OVX groups treated with saline (SAL), alendronate (ALE) (0.1 mg/kg), BG (62.5 mg/kg), RT (climbing a ladder with load) and the combination of BG + RT. All treatments were performed three times per week for 8 weeks starting 38 days after ovariectomy. OVX effectiveness was confirmed by a reduction in uterus mass (p 
ISSN:1369-7137
1473-0804
DOI:10.1080/13697137.2022.2077097