Submandibular gland epithelial development and the importance of junctions

Salivary glands consist of highly specialized epithelial cells that secrete the fluid, saliva, and/or transport saliva into the oral cavity. Saliva is essential to lubricate the oral cavity for food consumption and to maintain the hygiene of the oral cavity. In this review, we will focus on the form...

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Bibliographic Details
Published in:Tissue barriers 2023-10, Vol.11 (4), p.2161255-2161255
Main Authors: Bonnet, Hélène, Isidro Alonso, Carlos Agustin, Gupta, Indra R.
Format: Article
Language:English
Subjects:
cell junction
claudins
clefting
cytodifferentiation
Epithelial Cells
Intercellular Junctions
Review
Salivary Glands
Submandibular Gland
Tight Junctions
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Summary:Salivary glands consist of highly specialized epithelial cells that secrete the fluid, saliva, and/or transport saliva into the oral cavity. Saliva is essential to lubricate the oral cavity for food consumption and to maintain the hygiene of the oral cavity. In this review, we will focus on the formation of the epithelial cell lineage and the cell junctions that are essential for formation of saliva and maintenance of the epithelial barrier between the ducts that transport saliva and the extracellular environment.
ISSN:2168-8370
2168-8362
2168-8370
DOI:10.1080/21688370.2022.2161255