The effect of oral contraceptives on the apparent vitamin B6 status in some Sudanese women

1. In vitro activation of erythrocyte aspartate aminotransferase (EC 2.6.1.1) activity by pyridoxal phosphate was used to assess vitamin B4 nutritional status in forty Sudanese women taking combined, low-dose oral contraceptives (oestrogen-progestogen; OC) and in thirty healthy, non-pregnant women n...

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Bibliographic Details
Published in:British journal of nutrition 1986-09, Vol.56 (2), p.363-367
Main Authors: Salih, Eltayeb Y., Zein, Asma A., Bayoumi, Riad A.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aspartate Aminotransferases - metabolism
Biological and medical sciences
Birth control
Contraceptives, Oral - adverse effects
Enzyme Activation
Erythrocytes - enzymology
Female
Gynecology. Andrology. Obstetrics
Hormonal contraception
Humans
Medical sciences
Middle Aged
nutrient-drug interactions
nutritional status
Nutritional Status - drug effects
oral contraceptives
Papers of direct relevance to Clinical and Human Nutrition
Pyridoxal Phosphate
pyridoxine
Pyridoxine - metabolism
Reference Values
Sudan
Tropical medicine
vitamin deficiencies
women
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Summary:1. In vitro activation of erythrocyte aspartate aminotransferase (EC 2.6.1.1) activity by pyridoxal phosphate was used to assess vitamin B4 nutritional status in forty Sudanese women taking combined, low-dose oral contraceptives (oestrogen-progestogen; OC) and in thirty healthy, non-pregnant women not taking OC. 2. Fourteen (35%) out of forty OC users showed apparent vitamin B4 deficiency. 3. Side-effects associated with OC were more common among the apparently vitamin-B4-deficient OC users than among OC users and non-OC users not deficient in vitamin B4.
ISSN:0007-1145
1475-2662
DOI:10.1079/BJN19860117