Prostate cancer in older men : Special features of the diagnostics and treatment

Prostate cancer is the most frequent cancer in men. For localized prostate cancer, surgery and radiotherapy are the standard treatment, with active surveillance also used in low-risk cases. For advanced/metastatic disease, androgen deprivation treatment is carried out. Further options include inhibi...

Full description

Saved in:
Bibliographic Details
Published in:Zeitschrift für Gerontologie und Geriatrie 2023-07, Vol.56 (4), p.324
Main Authors: Degener, Stephan, Schmalz, Oliver, Tosch, Marco, Gödde, Daniel, von Rundstedt, Friedrich-Carl, Piroth, Marc D
Format: Article
Language:ger
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Prostate cancer is the most frequent cancer in men. For localized prostate cancer, surgery and radiotherapy are the standard treatment, with active surveillance also used in low-risk cases. For advanced/metastatic disease, androgen deprivation treatment is carried out. Further options include inhibitors of the androgen receptor axis and taxane-based chemotherapy. The avoidance of side effects should be considered, e.g., by dose adjustment. New options include poly(ADP-ribose) polymerase (PARP) inhibitors, and radioligand treatment. The existing guidelines only provide a few treatment recommendations for older patients; however, the treatment of older patients should primarily consider not only chronological age but also the patient's psychological and physical condition and preferences. In this context, the geriatric assessment represents an important instrument for determining the treatment strategy.
ISSN:1435-1269
DOI:10.1007/s00391-023-02194-z