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Gabapentinoids in Ireland 2010 to 2020: an observational study of trends in gabapentinoid prescribing, law enforcement drug seizures and post mortem toxicology
We explored trends in gabapentinoid prescribing, drug seizures and post mortem toxicology using a national pharmacy claims database, law enforcement drug seizures data and a population based post mortem toxicology database. Gabapentinoid prescribing rates per 100,000 eligible population (2010-2020),...
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Published in: | British journal of clinical pharmacology 2023-12 |
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Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Online Access: | Get full text |
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Summary: | We explored trends in gabapentinoid prescribing, drug seizures and post mortem toxicology using a national pharmacy claims database, law enforcement drug seizures data and a population based post mortem toxicology database.
Gabapentinoid prescribing rates per 100,000 eligible population (2010-2020), annual number of drug seizures involving gabapentinoids (2012-2020), and gabapentinoid detection (positive) rates per 100 post mortem toxicology case (2013-2020) were calculated. Negative binomial regression models were used to evaluate longitudinal trends for gabapentin and pregabalin separately.
Gabapentin (Adjusted Rate Ratio (ARR) 1.06, 95% CI 1.05-1.06, p |
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ISSN: | 1365-2125 |