Toxicity evaluation of novel imidacloprid nanoribbons, using somatic mutation and fitness indexes in Drosophila melanogaster

Nanoribbons of imidacloprid, a systemic and chloronicotinyl insecticide, were successfully synthesized by laser-induced fragmentation/exfoliation of imidacloprid powders suspended in water, with widths ranging from 160 to 470 nm, lengths in the micron scale, and thickness of a few atoms layers. The...

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Bibliographic Details
Published in:Journal of Toxicology and Environmental Health, Part A Part A, 2024-05, Vol.87 (9), p.398-418
Main Authors: Vidal, Luz M., Pimentel, Emilio, Escobar-Alarcón, Luis, Cruces, Martha P., Jiménez, Elizabeth, Suárez, Hugo, Leyva, Yosary
Format: Article
Language:English
Subjects:
Animals
Chronic exposure
D. melanogaster
Drosophila melanogaster
Drosophila melanogaster - genetics
Fruit flies
Genotoxicity
Imidacloprid
imidacloprid nanoribbons
insecticidal nanoparticles
Insecticides
Insecticides - toxicity
Insects
Larva
Larvae
Life span
Longevity
Male
Mutation
Nanoribbons
Nanotubes, Carbon - toxicity
Neonicotinoids - toxicity
Nitro Compounds
Productivity
Reduction
risk assessment
somatic mutation
Synthesis
Thickness
Viability
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Summary:Nanoribbons of imidacloprid, a systemic and chloronicotinyl insecticide, were successfully synthesized by laser-induced fragmentation/exfoliation of imidacloprid powders suspended in water, with widths ranging from 160 to 470 nm, lengths in the micron scale, and thickness of a few atoms layers. The aim of the present study was to examine the effects of acute and chronic exposure to imidacloprid (IMC) bulk and compare its effects with synthesized imidacloprid nanoribbons (IMCNR) on larval and adult viability, developmental time, olfactory capacity, longevity, productivity, and genotoxicity in Drosophila melanogaster. Larvae or adults were exposed at 0.01, 0.02, or 0.03 ppm to IMC or IMCNR. Results demonstrated that IMCNR produced a significant reduction in viability and olfactory ability. IMC did not significantly alter viability and olfactory ability. Similarly, marked differences on longevity were detected between treatment with IMC and IMCNR where the lifespan of males treated with IMC was significantly higher than control while IMCNR produced a reduction. As for productivity, developmental time, and genotoxicity, no marked differences were found between both forms of IMC.
ISSN:1528-7394
1087-2620
2381-3504
DOI:10.1080/15287394.2024.2316649