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Diffuse Large B-Cell Lymphoma with Aberrant Coexpression of CD5 and CD8 T-Cell Markers

Abstract Introduction: The expression of T-cell-associated antigens on diffuse large B-cell lymphoma (DLBCL) is uncommon. The coexpression of ≥2 T-cell-associated antigens on DLBCL is even rarer. This has been reported in the literature only a few times, most commonly coexpression of either CD5 or C...

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Bibliographic Details
Published in:Case reports in oncology 2024-01, Vol.17 (1), p.517-523
Main Authors: Fan, Janet, Thanedar, Sarita, Ovechko, Vasily, Jana, Bagi
Format: Article
Language:English
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Summary:Abstract Introduction: The expression of T-cell-associated antigens on diffuse large B-cell lymphoma (DLBCL) is uncommon. The coexpression of ≥2 T-cell-associated antigens on DLBCL is even rarer. This has been reported in the literature only a few times, most commonly coexpression of either CD5 or CD8 and a second, different T-cell marker. Case Presentation: This case report features a patient who presented with a rapidly evolving head and neck mass that displayed coexpression of CD5 and CD8. Conclusion: In this case report, we present the first case to our knowledge of DLBCL with coexpression of only CD5 and CD8.
ISSN:1662-6575
1662-6575
DOI:10.1159/000536571