Advances in biomimetic AIE nanoparticles for diagnosis and phototherapy

This minireview provides an overview of the recent advancements in the development of biomimetic Aggregation-Induced Emission (AIE) nanoparticles and their applications in disease diagnosis, phototherapy, and photoimmunotherapy. AIE nanoparticles can be engineered to enable efficient image-guided ph...

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Bibliographic Details
Published in:Nanoscale 2024-08, Vol.16 (31), p.1477-14715
Main Authors: Chau, Joe H. C, Lee, Michelle M. S, Yu, Eric Y, Kwok, Ryan T. K, Lam, Jacky W. Y, Sun, Jianwei, Tang, Ben Zhong
Format: Article
Language:English
Subjects:
Animals
Biomedical materials
Biomimetic materials
Biomimetic Materials - chemistry
Biomimetic Materials - therapeutic use
Diagnosis
Humans
Nanoparticles
Nanoparticles - chemistry
Nanoparticles - therapeutic use
Phototherapy
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Summary:This minireview provides an overview of the recent advancements in the development of biomimetic Aggregation-Induced Emission (AIE) nanoparticles and their applications in disease diagnosis, phototherapy, and photoimmunotherapy. AIE nanoparticles can be engineered to enable efficient image-guided photodynamic and photothermal therapies, however, challenges related to immune defense and target specificity persist. To overcome these, coating biomimetic materials on the surface of AIE nanoparticles, which mimic the features and functions of native cells, have emerged as a promising solution. This minireview will highlight the synthesis strategies and discuss the biomedical application of biomimetic AIE nanoparticles. An overview of the development of biomimetic AIE nanoparticles and their biomedical applications.
ISSN:2040-3364
2040-3372
2040-3372
DOI:10.1039/d4nr01417k