Persistent Methicillin-Resistant Staphylococcus aureus (MRSA) Nares Test Positivity During Initial Days of Systemic Anti-Staphylococcal Antimicrobial Therapy

The typical duration of positive nucleic acid tests for methicillin-resistant Staphylococcus aureus (MRSA) in the nares of patients receiving systemic anti-MRSA antimicrobials is unknown. In this study, hospitalized adult patients with an initial positive MRSA nares nucleic acid test prescribed syst...

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Bibliographic Details
Published in:American journal of infection control 2024-08
Main Authors: Wu, Maximillian S, Kufel, Wesley, Riddell, Scott, Steele, Jeff, Asiago-Reddy, Elizabeth
Format: Article
Language:English
Online Access:Get full text
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Summary:The typical duration of positive nucleic acid tests for methicillin-resistant Staphylococcus aureus (MRSA) in the nares of patients receiving systemic anti-MRSA antimicrobials is unknown. In this study, hospitalized adult patients with an initial positive MRSA nares nucleic acid test prescribed systemic anti-MRSA antimicrobials had follow-up testing done 48-96 hours later. A positive follow-up test was detected in 100/113 (88.5%), indicating that MRSA nares DNA tests still have utility for screening after patients have initiated anti-MRSA therapy.
ISSN:1527-3296