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Feasibility of position emission tomography derived endocardial wall strain: direct comparison with magnetic resonance using hybrid 13 N ammonia PETMR system

We aimed to evaluate the feasibility of positron emission tomography feature tracking (PETFT) for assessing endocardial wall strain by comparing it with cardiac magnetic resonance (CMR)-derived feature tracking (CMRFT). We enrolled 83 consecutive patients with coronary artery disease who underwent r...

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Bibliographic Details
Published in:Annals of nuclear medicine 2024-12
Main Authors: Katahira, Masataka, Fukushima, Kenji, Endo, Keiichiro, Kawakubo, Masateru, Ukon, Naoyuki, Yamakuni, Ryo, Kiko, Takatoyo, Shimizu, Takeshi, Ishii, Shiro, Yamaki, Takayoshi, Nagao, Michinobu, Ito, Hiroshi, Takeishi, Yasuchika
Format: Article
Language:English
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Summary:We aimed to evaluate the feasibility of positron emission tomography feature tracking (PETFT) for assessing endocardial wall strain by comparing it with cardiac magnetic resonance (CMR)-derived feature tracking (CMRFT). We enrolled 83 consecutive patients with coronary artery disease who underwent rest-pharmacologic stress N-ammonia PETMR (67 males, mean age 66 years). PETFT and CMRFT were obtained through simultaneous acquisition with electrocardiography-gated PET and cine-CMR. Global longitudinal and circumferential strain (GLS and GCS) were calculated. Correlations and Bland-Altman plots were employed to evaluate associations, bias, and 95% limit of agreement (LOA) between PETFT and CMRFT. PETFT and CMRFT showed significant correlations (R = 0.57 [95% CI 0.41-0.70], R = 0.71 [95% CI 0.58-0.80], R = 0.59 [95% CI 0.43-0.71], and R = 0.69 [95% CI 0.56-0.79] for rest GLS, rest GCS, stress GLS, and stress GCS, respectively; p 
ISSN:1864-6433