Loading…
TOXICOLOGICAL STUDIES ON A NEW MACROLIDE ANTIBIOTIC, MIDECAMYCIN ACETATE (MIOCAMYCIN): PART IV-5. TOXICITY OF METABOLITES OF MIOCAMYCIN: ACUTE TOXICITY OF Mb2 IN RATS
Miocamycin (MOM) is a derivative of midecamycin1), 2) and is metabolized into 4 main metabolites5). At previous study, LD0 values of Mb1, were estimated more than 5,000 mg/kg in male and female rats8). The object of this study was to evaluate acute toxicity in male and female rats after single oral...
Saved in:
Published in: | Japanese journal of antibiotics 1984/08/25, Vol.37(8), pp.1510-1512 |
---|---|
Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | Miocamycin (MOM) is a derivative of midecamycin1), 2) and is metabolized into 4 main metabolites5). At previous study, LD0 values of Mb1, were estimated more than 5,000 mg/kg in male and female rats8). The object of this study was to evaluate acute toxicity in male and female rats after single oral administration of Mb2, a metabolite of MOM. It is concluded that LD0 values of Mb2 were estimated more than 5,000 mg/kg. |
---|---|
ISSN: | 0368-2781 2186-5477 |
DOI: | 10.11553/antibiotics1968b.37.1510 |