Immunofluorescent localization of alpha fetoprotein in yolk sac carcinomas of the rat

alpha-Fetoprotein (AFP) was demonstrated by the immunofluorescent antibody staining technique in 1 primary and 3 transplantable yolk sac carcinomas of rats. AFP was observed only in structures with a characteristic endodermal appearance. This protein was not detected in embryonal carcinoma cells.20

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1976-12, Vol.57 (6), p.1375
Main Authors: Delacourt, M C, Sobis, H, Vandeputte, M
Format: Article
Language:English
Subjects:
alpha-Fetoproteins - analysis
Animals
Dysgerminoma - analysis
Dysgerminoma - pathology
Female
Fluorescent Antibody Technique
Neoplasms, Experimental - metabolism
Neoplasms, Experimental - pathology
Pregnancy
Rats
Rats, Inbred BN
Rats, Inbred Strains
Teratoma - analysis
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Description
Summary:alpha-Fetoprotein (AFP) was demonstrated by the immunofluorescent antibody staining technique in 1 primary and 3 transplantable yolk sac carcinomas of rats. AFP was observed only in structures with a characteristic endodermal appearance. This protein was not detected in embryonal carcinoma cells.20
ISSN:0027-8874
DOI:10.1093/jnci/57.6.1375