CLINICAL STUDIES ON CEFTAZIDIME IN PEDIATRIC FIELD

Ceftazidime (CAZ) is a newly developed cephalosporin. Clinical studies on this drug was carried out and the results were as follows. Twenty-nine patients (acute purulent tonsillitis 2, acute bronchitis 1, pneumonia 15, acute purulent lymphadenitis 2, pyoderma 1, skin abscess 2 and urinary tract infe...

Full description

Saved in:
Bibliographic Details
Published in:Japanese journal of antibiotics 1984/03/25, Vol.37(3), pp.349-354
Main Authors: AOYAMA, RYUZO, WAGA, SHINOBU, OHNISHI, AKIRA, IZUMI, YUKIO, KURONUMA, TADAYUKI, KAKIZAKI, YOSHIKI, NAGATA, KISHIRO, KUDO, MATAKA, OKANIWA, SHINICHI, SAWAGUCHI, HIROSHI, OKAMOTO, TADAATSU
Format: Article
Language:Japanese
Subjects:
Adolescent
Age Factors
Bacteria - isolation & purification
Bacterial Infections - drug therapy
Bacterial Infections - microbiology
Ceftazidime
Cephalosporins - administration & dosage
Cephalosporins - adverse effects
Cephalosporins - therapeutic use
Child
Child, Preschool
Drug Evaluation
Female
Humans
Infant
Infusions, Parenteral
Injections, Intravenous
Male
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Ceftazidime (CAZ) is a newly developed cephalosporin. Clinical studies on this drug was carried out and the results were as follows. Twenty-nine patients (acute purulent tonsillitis 2, acute bronchitis 1, pneumonia 15, acute purulent lymphadenitis 2, pyoderma 1, skin abscess 2 and urinary tract infection 6) were treated with CAZ in doses of 42-71mg/kg (mean 59mg/kg) divided 2-3 times per day for 3-10 days (mean 5.7 days) intravenously. The overall efficacy rate was 96.6%. As to adverse reaction, drug fever was observed in 1 patient. Abnormal laboratory data were noted in 4 cases (elevation of serum GOT, GPT and BUN in 1, elevation of serum GOT and GPT in 1, elevation of BUN in 1 and leukopenia in 1).
ISSN:0368-2781
2186-5477
DOI:10.11553/antibiotics1968b.37.349