Initial assessment of meptazinol in the treatment of the pain of myocardial infarction/unstable angina

Meptazinol, a new analgesic agent, was used to treat chest pain in patients admitted to a coronary care unit with suspected myocardial infarction or unstable angina. A pilot study showed that meptazinol was effective in relieving pain in 15 out of 22 subjects. There were no adverse haemodynamic effe...

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Bibliographic Details
Published in:Postgraduate medical journal 1983, Vol.59 Suppl 1, p.57
Main Authors: Sonecha, T, Abdel-Hadi, O, Besterman, E M, Kidner, P H
Format: Article
Language:English
Subjects:
Angina Pectoris - drug therapy
Azepines - therapeutic use
Cyclizine - therapeutic use
Humans
Injections, Intramuscular
Injections, Intravenous
Meptazinol - adverse effects
Meptazinol - therapeutic use
Myocardial Infarction - complications
Pain - drug therapy
Pain - etiology
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Summary:Meptazinol, a new analgesic agent, was used to treat chest pain in patients admitted to a coronary care unit with suspected myocardial infarction or unstable angina. A pilot study showed that meptazinol was effective in relieving pain in 15 out of 22 subjects. There were no adverse haemodynamic effects nor respiratory depression. Nausea and/or vomiting occurred with administration of the drug but as these symptoms may occur in patients with myocardial infarction who have not received any analgesia (Ingram et al., 1980), a cause and effect relationship cannot be inferred in this respect. The incidence of other side effects ascribed to meptazinol was low.
ISSN:0032-5473