Extrinsic allergic alveolitis caused by Penicillium frequentans. Review and presentation of a case

We present a case of extrinsic allergic alveolitis due to Penicillium frequentans exposure (suberosis) at a cork factory. Diagnosis was based on clinical history, a restrictive spirometric pattern, evidence of reticular-nodular lung infiltrates on the X-ray, intradermal skin tests with dual reaction...

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Bibliographic Details
Published in:Archivos de bronconeumología 1994-11, Vol.30 (9), p.462
Main Authors: Moral, A J, Arias, J, García, M A, Abengózar, R, Pérez-Carral, C, Senent, C J
Format: Article
Language:Spanish
Subjects:
Adult
Aspergillosis, Allergic Bronchopulmonary - diagnosis
Aspergillosis, Allergic Bronchopulmonary - diagnostic imaging
Aspergillosis, Allergic Bronchopulmonary - etiology
Humans
Male
Occupational Diseases - diagnosis
Occupational Diseases - etiology
Occupations
Penicillium
Radiography
Skin Tests
Spirometry
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Summary:We present a case of extrinsic allergic alveolitis due to Penicillium frequentans exposure (suberosis) at a cork factory. Diagnosis was based on clinical history, a restrictive spirometric pattern, evidence of reticular-nodular lung infiltrates on the X-ray, intradermal skin tests with dual reaction and precipitins-positive serum samples in the presence of the P. frequentans fungus. Although the patient refused to submit to a specific bronchial challenge, two natural challenges occurred when he once again happened to handle wet cork after leaving his previous job. The literature referring to this disease is reviewed.
ISSN:0300-2896