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Neonatal encephalitis caused by herpes simplex: immunohistochemical diagnosis of a case
The authors report the case of a female newborn infant, who had seizures and vesicles at the nose and inferior lip since the fifth day of life. CSF changes suggested an encephalitis. Signs of neurologic and respiratory deterioration were followed by death. Partial cranial autopsy showed a necrohemor...
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Published in: | Arquivos de neuro-psiquiatria 1993-09, Vol.51 (3), p.377 |
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container_title | Arquivos de neuro-psiquiatria |
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creator | Lamego, I Brinckmann, C Ciancio, A Minotto, R Hilbig, A Ulbrich-Kulczynski, J M Fontana, M H Barbosa-Coutinho, L M |
description | The authors report the case of a female newborn infant, who had seizures and vesicles at the nose and inferior lip since the fifth day of life. CSF changes suggested an encephalitis. Signs of neurologic and respiratory deterioration were followed by death. Partial cranial autopsy showed a necrohemorrhagic temporal encephalitis without intranuclear inclusions. Immunohistochemical examination by the avidin-biotin-peroxidase technique with polyclonal antibodies against Herpes simplex type 1 and type 2 was positive to type 2 Herpes simplex virus. |
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CSF changes suggested an encephalitis. Signs of neurologic and respiratory deterioration were followed by death. Partial cranial autopsy showed a necrohemorrhagic temporal encephalitis without intranuclear inclusions. Immunohistochemical examination by the avidin-biotin-peroxidase technique with polyclonal antibodies against Herpes simplex type 1 and type 2 was positive to type 2 Herpes simplex virus.</description><identifier>ISSN: 0004-282X</identifier><identifier>PMID: 8297244</identifier><language>por</language><publisher>Brazil</publisher><subject>Encephalitis - cerebrospinal fluid ; Encephalitis - etiology ; Encephalitis - pathology ; Female ; Herpes Simplex - cerebrospinal fluid ; Herpes Simplex - complications ; Herpes Simplex - pathology ; Humans ; Immunohistochemistry ; Infant, Newborn</subject><ispartof>Arquivos de neuro-psiquiatria, 1993-09, Vol.51 (3), p.377</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8297244$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lamego, I</creatorcontrib><creatorcontrib>Brinckmann, C</creatorcontrib><creatorcontrib>Ciancio, A</creatorcontrib><creatorcontrib>Minotto, R</creatorcontrib><creatorcontrib>Hilbig, A</creatorcontrib><creatorcontrib>Ulbrich-Kulczynski, J M</creatorcontrib><creatorcontrib>Fontana, M H</creatorcontrib><creatorcontrib>Barbosa-Coutinho, L M</creatorcontrib><title>Neonatal encephalitis caused by herpes simplex: immunohistochemical diagnosis of a case</title><title>Arquivos de neuro-psiquiatria</title><addtitle>Arq Neuropsiquiatr</addtitle><description>The authors report the case of a female newborn infant, who had seizures and vesicles at the nose and inferior lip since the fifth day of life. 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Immunohistochemical examination by the avidin-biotin-peroxidase technique with polyclonal antibodies against Herpes simplex type 1 and type 2 was positive to type 2 Herpes simplex virus.</description><subject>Encephalitis - cerebrospinal fluid</subject><subject>Encephalitis - etiology</subject><subject>Encephalitis - pathology</subject><subject>Female</subject><subject>Herpes Simplex - cerebrospinal fluid</subject><subject>Herpes Simplex - complications</subject><subject>Herpes Simplex - pathology</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Infant, Newborn</subject><issn>0004-282X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><recordid>eNqFzr0KwjAUhuEMSq0_lyDkBgohBtq6iuLkJOgmp-mpjeSPnhbs3duhu9M3vDzwLVgqhFCZLORzxdZEHyGkKss8YUkhy1wqlbLHDYOHHixHrzG2YE1viGsYCGtejbzFLiJxMi5a_B65cW7woTXUB92iM3qitYG3DzS50HCYMOGWLRuwhLt5N2x_Od9P1ywOlcP6FTvjoBtf85HDv_4DdQA_LA</recordid><startdate>199309</startdate><enddate>199309</enddate><creator>Lamego, I</creator><creator>Brinckmann, C</creator><creator>Ciancio, A</creator><creator>Minotto, R</creator><creator>Hilbig, A</creator><creator>Ulbrich-Kulczynski, J M</creator><creator>Fontana, M H</creator><creator>Barbosa-Coutinho, L M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>199309</creationdate><title>Neonatal encephalitis caused by herpes simplex: immunohistochemical diagnosis of a case</title><author>Lamego, I ; Brinckmann, C ; Ciancio, A ; Minotto, R ; Hilbig, A ; Ulbrich-Kulczynski, J M ; Fontana, M H ; Barbosa-Coutinho, L M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_82972443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>por</language><creationdate>1993</creationdate><topic>Encephalitis - cerebrospinal fluid</topic><topic>Encephalitis - etiology</topic><topic>Encephalitis - pathology</topic><topic>Female</topic><topic>Herpes Simplex - cerebrospinal fluid</topic><topic>Herpes Simplex - complications</topic><topic>Herpes Simplex - pathology</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Infant, Newborn</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lamego, I</creatorcontrib><creatorcontrib>Brinckmann, C</creatorcontrib><creatorcontrib>Ciancio, A</creatorcontrib><creatorcontrib>Minotto, R</creatorcontrib><creatorcontrib>Hilbig, A</creatorcontrib><creatorcontrib>Ulbrich-Kulczynski, J M</creatorcontrib><creatorcontrib>Fontana, M H</creatorcontrib><creatorcontrib>Barbosa-Coutinho, L M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Arquivos de neuro-psiquiatria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lamego, I</au><au>Brinckmann, C</au><au>Ciancio, A</au><au>Minotto, R</au><au>Hilbig, A</au><au>Ulbrich-Kulczynski, J M</au><au>Fontana, M H</au><au>Barbosa-Coutinho, L M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neonatal encephalitis caused by herpes simplex: immunohistochemical diagnosis of a case</atitle><jtitle>Arquivos de neuro-psiquiatria</jtitle><addtitle>Arq Neuropsiquiatr</addtitle><date>1993-09</date><risdate>1993</risdate><volume>51</volume><issue>3</issue><spage>377</spage><pages>377-</pages><issn>0004-282X</issn><abstract>The authors report the case of a female newborn infant, who had seizures and vesicles at the nose and inferior lip since the fifth day of life. 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subjects | Encephalitis - cerebrospinal fluid Encephalitis - etiology Encephalitis - pathology Female Herpes Simplex - cerebrospinal fluid Herpes Simplex - complications Herpes Simplex - pathology Humans Immunohistochemistry Infant, Newborn |
title | Neonatal encephalitis caused by herpes simplex: immunohistochemical diagnosis of a case |
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