Venous thrombosis on central catheters in oncology

Central venous catheters have considerably improved the comfort and safety of chemotherapy in cancer patients. However complications as thrombosis could occur and their incidence vary from 3.7 to 42% in oncology. Catheter placement induces modifications of vascular system with formation of a fibrin...

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Published in:La revue de medecine interne 1996, Vol.17 (10), p.821
Main Authors: Devie-Hubert, I, Carlier, M, Pozzo Di Borgo, C
Format: Article
Language:fre
Subjects:
Antineoplastic Agents - adverse effects
Catheterization, Central Venous - adverse effects
Humans
Neoplasms - complications
Neoplasms - drug therapy
Neoplasms - physiopathology
Risk Factors
Thrombophlebitis - etiology
Thrombophlebitis - physiopathology
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creator Devie-Hubert, I
Carlier, M
Pozzo Di Borgo, C
description Central venous catheters have considerably improved the comfort and safety of chemotherapy in cancer patients. However complications as thrombosis could occur and their incidence vary from 3.7 to 42% in oncology. Catheter placement induces modifications of vascular system with formation of a fibrin sleeve and/or a mural thrombus. Thrombosis origin is linked with catheter itself, its position and the biomaterial used. Hypercoagulable state in cancer results from the perturbation of blood flow, the composition of blood itself and the vessel wall, and increases the iatrogenic effects of indwelling catheters. Finally chemotherapy used in the treatment of cancer has been associated with an increased incidence of thromboembolic events, suggesting the proposal of an antithrombotic prophylaxis in cancer patients receiving chemotherapeutic agents through indwelling catheter.
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subjects Antineoplastic Agents - adverse effects
Catheterization, Central Venous - adverse effects
Humans
Neoplasms - complications
Neoplasms - drug therapy
Neoplasms - physiopathology
Risk Factors
Thrombophlebitis - etiology
Thrombophlebitis - physiopathology
title Venous thrombosis on central catheters in oncology
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