Lyell syndrome after amoxicillin administration in a 2 year old child

The authors report a toxic epidermal necrolysis (TEN) due to ampicillin (Agram) in a 2-year-old child. During the acute phase a septic syndrome occurred. The severity of the clinical and biological symptoms led to the administration of antibiotics, their systematic use remaining controversial. Recov...

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Bibliographic Details
Published in:Annales françaises d'anesthésie et de réanimation 1996, Vol.15 (7), p.1095
Main Authors: Surbled, M, Lejus, C, Milpied, B, Pannier, M, Souron, R
Format: Article
Language:fre
Subjects:
Amoxicillin - adverse effects
Anesthesia, General - methods
Animals
Anti-Bacterial Agents - adverse effects
Child, Preschool
Cricetinae
Humans
Intensive Care Units, Pediatric
Male
Stevens-Johnson Syndrome - etiology
Stevens-Johnson Syndrome - therapy
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Summary:The authors report a toxic epidermal necrolysis (TEN) due to ampicillin (Agram) in a 2-year-old child. During the acute phase a septic syndrome occurred. The severity of the clinical and biological symptoms led to the administration of antibiotics, their systematic use remaining controversial. Recovery was favourable in a paediatric burn centre. Sequelae were minor. TEN, the physiopathological mechanism of which remaining still unknown, may carry a vital risk.
ISSN:0750-7658