Early asymmetric neuropathy in primary Sjögren's syndrome

We report three female patients, 43, 47, and 50 years old, with a rare asymmetric form of clinically pure sensory neuropathy associated with primary Sjögren's syndrome. In all three patients glandular involvement was accompanied by peripheral nerve disease. Sensory conduction studies showed com...

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Bibliographic Details
Published in:Journal of neurology 1997-06, Vol.244 (6), p.383-387
Main Authors: DENISLIC, M, MEH, D
Format: Article
Language:English
Subjects:
Age of Onset
Autonomic Nervous System Diseases - pathology
Biological and medical sciences
Body Temperature Regulation - physiology
Female
Functional Laterality - physiology
Humans
Medical sciences
Middle Aged
Neural Conduction - physiology
Neurons, Afferent - pathology
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Sjogren's Syndrome - complications
Sjogren's Syndrome - pathology
Thermometers
Trigeminal Nerve - pathology
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Description
Summary:We report three female patients, 43, 47, and 50 years old, with a rare asymmetric form of clinically pure sensory neuropathy associated with primary Sjögren's syndrome. In all three patients glandular involvement was accompanied by peripheral nerve disease. Sensory conduction studies showed completely normal results in two of three patients. Yet assessment of thermal-specific thresholds and thermal pain thresholds, combined with autonomic function tests (sympathetic skin response and R-R interval variation) supported the clinical suspicion of peripheral nerve disorder. Sjögren's syndrome must be considered in asymmetric sensory neuropathies of unknown cause.
ISSN:0340-5354
1432-1459
DOI:10.1007/s004150050106