Sequence of a Human cDNA Encoding Cab45, a Ca2+-Binding Protein with Six EF-Hand Motifs

We report the sequence of a human cDNA encoding a deduced 362 amino acid protein with six EF-hand calcium-binding motifs. The protein is a likely human counterpart of the Cab45 protein recently identified in the 3T3-L1 mouse adipocyte cell line [Scherer et al. (1996), J. Cell Biol. 133, 257-268], di...

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Bibliographic Details
Published in:DNA sequence 1997, Vol.7 (3-4), p.217-220
Main Authors: Koivu, Tapio, Latinen, Saara, Riento, Kirsi, Olkkonen, Vesa M.
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Base Sequence
Binding Sites
Blotting, Northern
Calcium-binding protein
Calcium-Binding Proteins - genetics
Calcium-Binding Proteins - metabolism
Glycoproteins - genetics
Glycoproteins - metabolism
golgi complex
human cDNA
Humans
Mice
Molecular Sequence Data
northern analysis
secretory pathway
sequence analysis
Sequence Analysis, DNA
Sequence Homology, Amino Acid
Tissue Distribution
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Summary:We report the sequence of a human cDNA encoding a deduced 362 amino acid protein with six EF-hand calcium-binding motifs. The protein is a likely human counterpart of the Cab45 protein recently identified in the 3T3-L1 mouse adipocyte cell line [Scherer et al. (1996), J. Cell Biol. 133, 257-268], displaying 87% aa and 83% nt identity with this sequence. The mRNA for human Cab45 is detected ubiquitously in tissue Northern blots.
ISSN:1042-5179
1029-2365
DOI:10.3109/10425179709034038