Effect of carbohydrate ingestion on adipose tissue lipolysis during long-lasting exercise in trained men

• Published in: Journal of applied physiology (1985) 1998-05, Vol.84 (5), p.1627-1632
• Main Authors: De Glisezinski, I, Harant, I, Crampes, F, Trudeau, F, Felez, A, Cottet-Emard, J. M, Garrigues, M, Riviere, D
• Format: Article
• Language: English
• Subjects: Adipose Tissue - metabolism; Adult; Biological and medical sciences; Blood Glucose - metabolism; Carbohydrates - pharmacology; Catecholamines - blood; Fatty Acids - blood; Feeding. Feeding behavior; Fundamental and applied biological sciences. Psychology; Glycerol - blood; Humans; Insulin - blood; Lactic Acid - blood; Lipid Mobilization - physiology; Lipolysis - physiology; Male; Microdialysis - methods; Middle Aged; Physical Exertion - physiology; Sucrose - pharmacology; Vertebrates: anatomy and physiology, studies on body, several organs or systems
• ISSN: 8750-7587; 1522-1601
• DOI: 10.1152/jappl.1998.84.5.1627

1  Laboratoire des Adaptations de l'Organisme à l'Exercice Musculaire, Service d'Exploration de la Fonction Respiratoire et de Médecine du Sport, Centre Hospitalier Universitaire Purpan, 31059 Toulouse Cedex, France; 2  Département des Sciences de l'Activite Physique, Université du Quebec à Trois-Rivières, Trois-Rivières, Quebec, Canada G9A 5H7; 3  Laboratoire de Physiologie de l'Environnement, Université Claude Bernard Lyon Grange-Blanche, 69373 Lyon Cedex 08; and 4  Institut National de la Santé et de la Recherche Médicale Unité 317, Institut Louis Bugnard, Centre Hospitalier Universitaire Rangueil, 31054 Toulouse Cedex, France To study whether sucrose administration acts on lipid mobilization during prolonged exercise, we used subcutaneous abdominal adipose tissue microdialysis in eight well-trained subjects submitted at random to two 100-min exercises (50% maximal aerobic power) on separate days. After 50 min of exercise, the subjects ingested either a sucrose solution (0.75 g/kg body wt) or water. By using a microdialysis probe, dialysate was obtained every 10 min from the subjects at rest, during exercise, and during a 30-min recovery period. During exercise without sucrose, plasma and dialysate glycerol increased significantly. With sucrose, the response was significantly lower for dialysate glycerol ( P