Association between Age at Helicobacter pylori Eradication and the Risk of Gastric Cancer Stratified by Family History of Gastric Cancer: A Nationwide Population-Based Study

This study compares the risk of GC according to age at eradication, stratified based on the presence of family history of GC using a population-based large cohort. We analyzed individuals who underwent GC screening between 2013 and 2014 and received eradication therapy before screening. Among 1,888,...

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Bibliographic Details
Published in:Cancers 2023-03, Vol.15 (5), p.1604
Main Authors: Jung, Yoon Suk, Tran, Mai Thi Xuan, Song, Huiyeon, Park, Boyoung, Moon, Chang Mo
Format: Article
Language:English
Subjects:
Age
Body mass index
Codes
Comorbidity
Disease
Eradication
Family medical history
Gastric cancer
Gastrointestinal surgery
Medical research
Medical screening
Population studies
Population-based studies
Questionnaires
Tumors
Ulcers
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Summary:This study compares the risk of GC according to age at eradication, stratified based on the presence of family history of GC using a population-based large cohort. We analyzed individuals who underwent GC screening between 2013 and 2014 and received eradication therapy before screening. Among 1,888,815 -treated patients, 2610/294,706 and 9332/1,594,109 patients with and without a family history of GC, respectively, developed GC. After adjusting for confounders, including age at screening, the adjusted hazard ratios (95% confidence intervals) for GC comparison, 70-74, 65-69, 60-64, 55-59, 50-54, 45-49, and
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers15051604