Effects of cytokine hemadsorption as salvage therapy on common laboratory parameters in patients with life-threatening COVID-19

The COVID-19 pandemic has led to emergency approval of treatment modalities unusual for viruses, such as therapeutic cytokine Hemadsorption(HA). This study aims to investigate the experience of salvage HA therapy and the effect of HA on routine laboratory tests. Life-threatening COVID-19 patients fo...

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Bibliographic Details
Published in:Transfusion and apheresis science 2023-06, Vol.62 (3), p.103701-103701, Article 103701
Main Authors: Uysal, Serhat, Merter, Mustafa, Uysal, Ayşe, Akbulut, Ayhan
Format: Article
Language:English
Subjects:
COVID-19
Creactive protein
Cytokine adsorption
Fibrinogen
Hemadsorption
Lactate dehydrogenase
Platelet
Therapeutic adsorption
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Summary:The COVID-19 pandemic has led to emergency approval of treatment modalities unusual for viruses, such as therapeutic cytokine Hemadsorption(HA). This study aims to investigate the experience of salvage HA therapy and the effect of HA on routine laboratory tests. Life-threatening COVID-19 patients followed up between April 2020 and October 2022 who underwent HA salvage therapy were retrospectively enrolled. Data derived from the medical records were evaluated to meet the assumptions of statistical tests, and those that met the relevant statistical rules were selected for further analysis. Tests of Wilcoxon, Paired-T, and repeated measures-ANOVA were used to analyse the laboratory tests performed before and after HA among the surviving and nonsurviving patients. P 
ISSN:1473-0502
1878-1683
1473-0502
DOI:10.1016/j.transci.2023.103701