Comparison of serum 1,25-dihydroxycholecalciferol concentrations in rheumatoid arthritis and osteoarthrosis

We have previously compared 25-hydroxycholecalciferol levels in the serum of patients with osteoarthrosis and rheumatoid arthritis, finding no significant difference between the circulating levels of this hormone. We have now estimated 1,25-dihydroxycholecalciferol levels on stored sera from the sam...

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Bibliographic Details
Published in:Annals of the rheumatic diseases 1982-06, Vol.41 (3), p.257-258
Main Authors: Bird, H A, Wright, V, Hennes, U, Theiss, E
Format: Article
Language:English
Subjects:
Aged
Arthritis, Rheumatoid - blood
Calcitriol - blood
Female
Humans
Male
Middle Aged
Osteoarthritis - blood
Sunlight
Vitamin D - administration & dosage
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Summary:We have previously compared 25-hydroxycholecalciferol levels in the serum of patients with osteoarthrosis and rheumatoid arthritis, finding no significant difference between the circulating levels of this hormone. We have now estimated 1,25-dihydroxycholecalciferol levels on stored sera from the same groups of patients and found no significant difference in the levels of this hormone between the 2 groups. The osteopenia that distinguishes rheumatoid arthritis from osteoarthrosis is not the result of altered levels of systemic 25OHD3 or of 1,25(OH)2D3. Local factors may be more important in its pathogenesis.
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.41.3.257