Synovial fluid lactate levels in septic and non-septic arthritides

Lactate concentration was studied in 383 synovial fluid specimens from patients with various arthritides. The highest concentrations of lactate occurred in non-gonococcal septic synovial fluids. High values were recorded in seropositive rheumatoid arthritis and crystal-induced arthritides, medium va...

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Bibliographic Details
Published in:Annals of the rheumatic diseases 1984-10, Vol.43 (5), p.742-745
Main Authors: Gobelet, C, Gerster, J C
Format: Article
Language:English
Subjects:
Arthritis - metabolism
Arthritis, Infectious - metabolism
Arthritis, Reactive - metabolism
Arthritis, Rheumatoid - metabolism
Bacterial arthritis and osteitis
Bacterial diseases
Biological and medical sciences
Gonorrhea - metabolism
Hemarthrosis - metabolism
Human bacterial diseases
Humans
Hydrogen-Ion Concentration
Infectious diseases
Lactates - analysis
Lactic Acid
Medical sciences
Osteoarthritis - metabolism
Spondylitis, Ankylosing - metabolism
Synovial Fluid - analysis
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Summary:Lactate concentration was studied in 383 synovial fluid specimens from patients with various arthritides. The highest concentrations of lactate occurred in non-gonococcal septic synovial fluids. High values were recorded in seropositive rheumatoid arthritis and crystal-induced arthritides, medium values in synovial fluids from seronegative rheumatoid arthritis, seronegative spondylarthritides, gonococcal arthritis and haemarthrosis, and the lowest values in aspirates from osteoarthrotic joints. There was a positive correlation between synovial pH and lactic acid concentration. These data suggest that determination of lactate in synovial fluid can be valuable in the rapid exclusion of septic arthritis. Its value for differentiating between other inflammatory arthritides is discussed.
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.43.5.742