TEMPORAL ARTERY BIOPSY: A TECHNICAL GUIDE AND REVIEW OF ITS IMPORTANCE & INDICATIONS

Temporal artery biopsy (TAB) is a surgical procedure that enables the histological diagnosis of giant cell arteritis (GCA). Performing a TAB requires expertise and a precise approach. Nevertheless, available data supports the value of tissue diagnosis in managing GCA. The current therapeutic recomme...

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Bibliographic Details
Published in:Survey of ophthalmology 2023-01, Vol.68 (1), p.104-112
Main Authors: PARREAU, Simon, LIOZON, Eric, CHEN, John J, CURUMTHAULLEE, Muhammad F, FAUCHAIS, Anne-Laure, WARRINGTON, Kenneth, LY, Kim-Heang, WEYAND, Cornelia M
Format: Article
Language:English
Subjects:
Biopsy
Giant cell arteritis
Giant Cell Arteritis - complications
Giant Cell Arteritis - diagnosis
Humans
Immunosuppressive Agents - therapeutic use
Retrospective Studies
Sensitivity and Specificity
Temporal Arteries - pathology
Temporal artery biopsy
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Summary:Temporal artery biopsy (TAB) is a surgical procedure that enables the histological diagnosis of giant cell arteritis (GCA). Performing a TAB requires expertise and a precise approach. Nevertheless, available data supports the value of tissue diagnosis in managing GCA. The current therapeutic recommendation for GCA is long-term glucocorticoid therapy, with an increasing emphasis on the addition of immunosuppressants/biotherapies. Though effective, immunosuppressants and other such biotherapies may put the patient at more risk. Optimizing the diagnosis through tissue evaluation is therefore important in weighing the risks and benefits of initiating therapeutic intervention.We evaluate the evidence supporting the importance of TAB and its indications. We also describe what technical approaches should be used to maximize sensitivity and to avoid possible complications during the procedure.
ISSN:0039-6257
1879-3304
DOI:10.1016/j.survophthal.2022.08.008