Relationship between Habitual Caffeine Consumption, Attentional Performance, and Individual Alpha Frequency during Total Sleep Deprivation

(1) Background: Caffeine is a psychostimulant that is well known to mitigate the deleterious effects of sleep debt. Our aim was to assess the effects of acute caffeine intake on cognitive vulnerability and brain activity during total sleep deprivation (TSD), taking into account habitual caffeine con...

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Bibliographic Details
Published in:International journal of environmental research and public health 2023-03, Vol.20 (6), p.4971
Main Authors: Quiquempoix, Michael, Drogou, Catherine, Erblang, Mégane, Van Beers, Pascal, Guillard, Mathias, Tardo-Dino, Pierre-Emmanuel, Rabat, Arnaud, Léger, Damien, Chennaoui, Mounir, Gomez-Merino, Danielle, Sauvet, Fabien
Format: Article
Language:English
Subjects:
Analysis
Attention
Caffeine
Caffeine - pharmacology
Cognitive science
Consumers
Consumption
Correlation analysis
EEG
Electroencephalography
Humans
Laboratories
Placebos
Psychomotor Performance
Questionnaires
Reaction Time
Sleep
Sleep and wakefulness
Sleep Deprivation
Sleepiness
Vigilance
Wakefulness
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Summary:(1) Background: Caffeine is a psychostimulant that is well known to mitigate the deleterious effects of sleep debt. Our aim was to assess the effects of acute caffeine intake on cognitive vulnerability and brain activity during total sleep deprivation (TSD), taking into account habitual caffeine consumption. (2) Methods: Thirty-seven subjects were evaluated in a double-blind, crossover, total sleep deprivation protocol with caffeine or placebo treatment. Vigilant attention was evaluated every six hours during TSD using the psychomotor vigilance test (PVT) with EEG recordings. The influence of habitual caffeine consumption was analyzed by categorizing subjects into low, moderate, and high consumers. (3) Results: The PVT reaction time (RT) increased during TSD and was lower in the caffeine condition vs. the placebo condition. The RT was shorter in the low-caffeine consumers compared to moderate and high consumers, regardless of conditions and treatments. The TSD-related increase in EEG power was attenuated by acute caffeine intake independently of habitual caffeine consumption, and the individual alpha frequency (IAF) was lower in the high-consumption group. The IAF was negatively correlated with daytime sleepiness. Moreover, a correlation analysis showed that the higher the daily caffeine consumption, the higher the RT and the lower the IAF. (4) Conclusions: A high level of habitual caffeine consumption decreases attentional performance and alpha frequencies, decreasing tolerance to sleep deprivation.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph20064971