Prevention of malignant digestive system tumors should focus on the control of chronic inflammation

Chronic inflammation, through a variety of mechanisms, plays a key role in the occurrence and development of digestive system malignant tumors (DSMTs). In this study, we feature and provide a comprehensive understanding of DSMT prevention strategies based on preventing or controlling chronic inflamm...

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Bibliographic Details
Published in:World journal of gastrointestinal oncology 2023-03, Vol.15 (3), p.389-404
Main Authors: Zhang, Yue-Hua, Chen, Xiao-Lin, Wang, Yi-Ran, Hou, Yu-Wei, Zhang, Yao-Dong, Wang, Kai-Juan
Format: Article
Language:English
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Summary:Chronic inflammation, through a variety of mechanisms, plays a key role in the occurrence and development of digestive system malignant tumors (DSMTs). In this study, we feature and provide a comprehensive understanding of DSMT prevention strategies based on preventing or controlling chronic inflammation. The development and evaluation of cancer prevention strategies is a longstanding process. Cancer prevention, especially in the early stage of life, should be emphasized throughout the whole life course. Issues such as the time interval for colon cancer screening, the development of direct-acting antiviral drugs for liver cancer, and the vaccine all need to be explored in long-term, large-scale experiments in the future.
ISSN:1948-5204
1948-5204
DOI:10.4251/wjgo.v15.i3.389