Current State of the Art and Next Generation of Materials for a Customized IntraOcular Lens according to a Patient-Specific Eye Power

Intraocular lenses (IOLs) are commonly implanted after surgical removal of a cataractous lens. A variety of IOL materials are currently available, including collamer, hydrophobic acrylic, hydrophilic acrylic, PHEMA copolymer, polymethylmethacrylate (PMMA), and silicone. High-quality polymers with di...

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Bibliographic Details
Published in:Polymers 2023-03, Vol.15 (6), p.1590
Main Authors: Vacalebre, Martina, Frison, Renato, Corsaro, Carmelo, Neri, Fortunato, Santoro, Antonio, Conoci, Sabrina, Anastasi, Elena, Curatolo, Maria Cristina, Fazio, Enza
Format: Article
Language:English
Subjects:
Astigmatism
Biocompatibility
Cataracts
Copolymers
Design
Evolution
Eye
Haptics
Intraocular lenses
Light
Market shares
Microsurgery
Optical properties
Optics
Polymethylmethacrylate
Quality standards
Refractivity
Review
State of the art
Surgery
Visual acuity
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Summary:Intraocular lenses (IOLs) are commonly implanted after surgical removal of a cataractous lens. A variety of IOL materials are currently available, including collamer, hydrophobic acrylic, hydrophilic acrylic, PHEMA copolymer, polymethylmethacrylate (PMMA), and silicone. High-quality polymers with distinct physical and optical properties for IOL manufacturing and in line with the highest quality standards on the market have evolved to encompass medical needs. Each of them and their packaging show unique advantages and disadvantages. Here, we highlight the evolution of polymeric materials and mainly the current state of the art of the unique properties of some polymeric systems used for IOL design, identifying current limitations for future improvements. We investigate the characteristics of the next generation of IOL materials, which must satisfy biocompatibility requirements and have tuneable refractive index to create patient-specific eye power, preventing formation of posterior capsular opacification.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym15061590