Pneumocystis Pneumonia With Multiple Centrilobular Pulmonary Nodules and Lack of Ground-Glass Attenuation on High-Resolution Computed Tomography

pneumonia (PCP) typically presents with diffuse ground-glass attenuation (GGA) in both lungs on high-resolution CT (HRCT). While other radiological features, including cysts and air-space consolidation, may be found, the absence of GGA has a high negative predictive value for PCP in patients with AI...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-02, Vol.15 (2), p.e35565
Main Authors: Takaki, Ryuichiro, Komiya, Kosaku, Fujishima, Nobuhiro, Yamanaka, Marimu, Yokoyama, Atsushi, Hiramatsu, Kazufumi, Kadota, Jun-Ichi
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Case reports
HIV
Human immunodeficiency virus
Infectious Disease
Infectious diseases
Pulmonology
Radiology
Tuberculosis
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Summary:pneumonia (PCP) typically presents with diffuse ground-glass attenuation (GGA) in both lungs on high-resolution CT (HRCT). While other radiological features, including cysts and air-space consolidation, may be found, the absence of GGA has a high negative predictive value for PCP in patients with AIDS. We report a case of PCP in a male patient who visited our hospital with a subacute, non-productive cough. He had never been diagnosed with an HIV infection. Although his HRCT scan revealed multiple centrilobular nodules without GGA, was detected in the bronchoalveolar lavage (BAL), and no other additional pathogens were identified. The patient was diagnosed with PCP associated with AIDS after a high plasma HIV-RNA titer and low CD4+ cell count were confirmed. Physicians need to be aware of this atypical radiological presentation of PCP associated with AIDS.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.35565