Role of bio-electrochemical technology for enzyme activity stimulation in high-consumption pharmaceuticals biodegradation

Active pharmaceutical ingredients (APIs) and their intermediate residues have recently been considered a serious concern. Among technologies, bio-electrochemical technologies (BETs) have stimulated the production of bio-electrical energy. This review aims to examine the benefit and mechanism of BETs...

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Bibliographic Details
Published in:3 Biotech 2023-05, Vol.13 (5), p.119-119, Article 119
Main Authors: Moghiseh, Zohreh, Xiao, Yong, Kalantar, Mojtaba, Barati, Barat, Ghahrchi, Mina
Format: Article
Language:English
Subjects:
Agriculture
Analgesics
Biodegradation
Bioelectricity
Bioinformatics
Biomaterials
Bioreactors
Biotechnology
Cancer Research
Chemistry
Chemistry and Materials Science
Contaminants
Detoxification
Drugs
Electron transfer
Enzymatic activity
Enzyme activity
Enzymes
Inflammation
Intermediates
Oxidation
Pharmaceutical industry
Pharmaceuticals
Phenolic compounds
Review
Review Article
Stem Cells
Stimulation
Wastewater
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Summary:Active pharmaceutical ingredients (APIs) and their intermediate residues have recently been considered a serious concern. Among technologies, bio-electrochemical technologies (BETs) have stimulated the production of bio-electrical energy. This review aims to examine the benefit and mechanism of BETs on the degradation of high-consumption pharmaceutical compounds, including antibiotic, anti-inflammatory, and analgesic drugs, and the stimulation of enzymes induced in a bioreactor. Moreover, intermediates and the proposed pathways of pharmaceutical compound biodegradation in BETs are to be explained in this review. According to studies performed exclusively, the benefit of BETs is using bio-electroactive microbes to mineralize recalcitrant pharmaceutical contaminants by promoting enzyme activity and energy. Since BETs use the electron transfer chain between bio-anode/-cathode and pharmaceuticals, the enzyme activity is essential in the oxidation and reduction of phenolic rings of drugs and the ineffective detoxification of effluent from the treatment plant. This study is suggested a vital and influential role of BETs in mineralizing and enzyme induction in bioreactors. Eventually, a content of future developments or outlooks of BETs are propounded to improve the pharmaceutical industries’ wastewater problems.
ISSN:2190-572X
2190-5738
DOI:10.1007/s13205-023-03539-6