Prostatic cancer and chronic respiratory and renal disease in British cadmium workers: a case control study

Deaths due to prostatic cancer, renal cancer, bronchitis or emphysema, and nephritis or nephrosis in three cohorts of cadmium workers have been investigated in a case-control study. Evidence of an association of risk for these diseases with intensity and duration of exposure to cadmium was sought. T...

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Bibliographic Details
Published in:British Journal of Industrial Medicine 1985-08, Vol.42 (8), p.540-545
Main Authors: Armstrong, B G, Kazantzis, G
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Bronchial diseases
Bronchitis
Cadmium
Cadmium - adverse effects
Cancer
Case control studies
Emphysema
Humans
Kidney Diseases - chemically induced
Kidney Diseases - mortality
Kidney Neoplasms - chemically induced
Lung Diseases, Obstructive - chemically induced
Lung Diseases, Obstructive - mortality
Male
Medical sciences
Middle Aged
Nephritis
Nephrology. Urinary tract diseases
Nephrosis
Occupational Diseases - chemically induced
Occupational Diseases - mortality
Prostate cancer
Prostatic Neoplasms - chemically induced
Prostatic Neoplasms - mortality
Risk
Statistical significance
Tumors of the urinary system
United Kingdom
Urinary tract. Prostate gland
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Summary:Deaths due to prostatic cancer, renal cancer, bronchitis or emphysema, and nephritis or nephrosis in three cohorts of cadmium workers have been investigated in a case-control study. Evidence of an association of risk for these diseases with intensity and duration of exposure to cadmium was sought. The only clearly statistically significant finding was of an association of deaths coded as bronchitis or emphysema with "high" levels of exposure to cadmium fume, which was related also to duration of exposure. There was suggestive evidence also (p congruent to 0.10) of an increased risk for nephritis or nephrosis after high exposure. Marginally increased risks were observed for prostatic cancer after high or "medium" exposure, but these were not statistically significant.
ISSN:0007-1072
1351-0711
1470-7926
DOI:10.1136/oem.42.8.540