The Association of Anesthesia Type and Neonatal Outcomes Following Category-1 Cesarean Delivery: A Retrospective Cohort Study

Objectives Neuraxial anesthesia is the preferred anesthesia technique for cesarean delivery due to a decreased risk of adverse events. However, general anesthesia is often employed during emergent cesarean deliveries to achieve a shorter decision-to-delivery interval. The objective of this study was...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-03, Vol.15 (3), p.e35910-e35910
Main Authors: Skoog, Carl M, Katzer, Joel F, Wendt, Linder H, Ituk, Unyime
Format: Article
Language:English
Subjects:
Anesthesia
Anesthesiology
Apgar score
Birth weight
Blood pressure
Catheters
Cesarean section
Childbirth & labor
Cohort analysis
Demographics
Drug dosages
Epidural
Fetuses
Gestational age
Intubation
Length of stay
Medical records
Newborn babies
Obstetrics
Obstetrics/Gynecology
Pediatrics
Skin
Umbilical cord
Variables
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Summary:Objectives Neuraxial anesthesia is the preferred anesthesia technique for cesarean delivery due to a decreased risk of adverse events. However, general anesthesia is often employed during emergent cesarean deliveries to achieve a shorter decision-to-delivery interval. The objective of this study was to determine if the conversion of epidural labor analgesia to surgical anesthesia for a category-1 cesarean delivery is associated with significant neonatal morbidity. Study design This was a retrospective cohort study of all intrapartum category-1 cesarean deliveries performed at an academic tertiary care institution between August 2016 and July 2021. The primary outcome was neonatal morbidity, defined as a composite of neonatal umbilical artery pH < 7.10 and/or 5-min Apgar score < 7, and/or neonatal intensive care unit admission. A multivariate regression analysis was performed to control for the presence of covariates and examine the degree to which they influenced the outcome. Results A total of 185 mother-neonate pairs qualified for inclusion, of which 23 had cesarean delivery under general anesthesia and 162 under epidural anesthesia. There was no significant difference in adverse neonatal outcomes between category-1 cesarean deliveries done under general anesthesia compared to epidural anesthesia (47% vs 35%, p = 0.3). The incidence of umbilical arterial pH < 7.10 was higher in the general anesthesia group compared to the epidural anesthesia group (35% vs 12%, p = 0.018). The multivariate regression model showed that gestational age (OR = 0.63; 95% CI = 0.51-0.75, p =
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.35910