Esophageal achalasia, diagnosed through the repeated manometry, alleviated using benzodiazepine: A case report

• Published in: Medicine (Baltimore) 2023-04, Vol.102 (14), p.e33494-e33494
• Main Authors: Nishi, Ryusei, Amitani, Haruka, Hamada, Kazumasa, Fukumoto, Takamasa, Kato, Ryuichi, Yamamoto, Takako, Fuku, Yuuki, Sagiyama, Kenichiro, Asakawa, Akihiro
• Format: Article
• Language: English
• Subjects: Benzodiazepines; Clinical Case Report; Deglutition Disorders; Esophageal Achalasia - diagnosis; Esophageal Achalasia - drug therapy; Esophageal Sphincter, Lower; Humans; Male; Manometry - methods; Middle Aged
• ISSN: 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000033494

Idiopathic achalasia is an esophageal peristaltic dysfunction of the lower esophageal sphincter (LES). The initial symptom is progressive dysphagia. However, due to its rarity, it is often misdiagnosed as an esophageal disorder. High LES pressure on esophageal manometry is an essential finding for the diagnosis. A 55-year-old man was hospitalized with saliva-like vomitus, stuck-in-throat feeling of dysphagia, and weight loss. On initial admission, gastrointestinal endoscopy, esophageal manometry, laboratory tests, and physical examination results were within normal limits. Initially, the patient was diagnosed with globus sensation and recovered with medication. However, the symptoms recurred. He requested another examination on the second admission and was diagnosed with achalasia based on repeat esophageal manometry. The patient recovered after surgical treatment. When patients still suffer from these symptoms, there is a need to reconsider achalasia, even if it is initially excluded from the differential diagnosis. Medication is not a radical treatment; however, it sometimes ameliorates symptoms. Moreover, the psychosomatic approach can be useful in such cases.