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Epidemiology of respiratory syncytial virus in hospitalized children with community-acquired pneumonia in Guangzhou: a 10-year study

Respiratory syncytial virus (RSV) is one of the most common virus causing community-acquired pneumonia (CAP) in children. To guide the prevention, diagnosis and treatment of RSV, we aimed to analyze the epidemiology of RSV in hospitalized children with CAP. A total of 9,837 hospitalized children (≤1...

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Bibliographic Details
Published in:Journal of thoracic disease 2023-03, Vol.15 (3), p.967-976
Main Authors: Li, Yuan, Zhai, Yingying, Lin, Yuneng, Lu, Chengyu, He, Zhentao, Wu, Shangzhi, Yang, Cui, Zhou, Rong, Liu, Wenkuan, Chen, Dehui
Format: Article
Language:English
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Summary:Respiratory syncytial virus (RSV) is one of the most common virus causing community-acquired pneumonia (CAP) in children. To guide the prevention, diagnosis and treatment of RSV, we aimed to analyze the epidemiology of RSV in hospitalized children with CAP. A total of 9,837 hospitalized children (≤14 years old) with CAP from January 2010 to December 2019 were reviewed. Using the real-time polymerase chain reaction (RT-PCR), the oropharyngeal swab specimens were collected and tested for RSV, influenza virus A (INFA), influenza virus B (INFB), parainfluenza virus (PIV), enterovirus (EV), coronavirus (CoV), human metapneumovirus (HMPV), human bocavirus (HBoV), human rhinovirus (HRV), and adenovirus (ADV) for each patient. The detection rate of RSV was 15.3% (1,507/9,837). From 2010 to 2019, the RSV detection rate showed a wavy change (χ =166.982, P
ISSN:2072-1439
2077-6624
DOI:10.21037/jtd-22-331