Blood transfusion in aortic root surgery impairs midterm survival

To evaluate the effect of perioperative allogeneic packed red blood cell (RBC) transfusion during aortic root replacement. We reviewed patients undergoing aortic root replacement at our institution between March 2014 and April 2020. In total, 760 patients underwent aortic root replacement, of whom 4...

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Bibliographic Details
Published in:JTCVS open 2023-03, Vol.13, p.9-19
Main Authors: Dalal, Alex R., Pedroza, Albert J., Krishnan, Aravind, Min, Yan, Tognozzi, Emily, Yokoyama, Nobu, Nakamura, Ken, Mitchel, Olivia R., Baiocchi, Michael, Woo, Y. Joseph, MacArthur, John W., Fischbein, Michael P.
Format: Article
Language:English
Subjects:
Adult: Aorta
aortic root replacement
blood transfusion
midterm survival
outcomes
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Summary:To evaluate the effect of perioperative allogeneic packed red blood cell (RBC) transfusion during aortic root replacement. We reviewed patients undergoing aortic root replacement at our institution between March 2014 and April 2020. In total, 760 patients underwent aortic root replacement, of whom 442 (58%) received a perioperative RBC transfusion. Propensity score matching was used to account for baseline and operative differences resulting in 159 matched pairs. All-cause mortality was assessed with Kaplan–Meier curves. Data were obtained from our institutional Society of Thoracic Surgeons database and chart review. After propensity score matching, the RBC-transfused and -nontransfused groups were similar for all preoperative characteristics. Cardiopulmonary bypass time, crossclamp time, and lowest operative temperature were similar between the transfused and nontransfused groups (standardized mean difference
ISSN:2666-2736
2666-2736
DOI:10.1016/j.xjon.2023.01.006