Loading…

Rheumatoid arthritis and Hailey‐Hailey disease treated with methotrexate

We report a rare case of long‐standing Hailey‐Hailey disease in a Caucasian Portuguese 69‐year‐old woman, recently diagnosed with rheumatoid arthritis. The patient's skin lesions remained active and exudative despite topical and oral treatments with corticosteroids, tetracyclines, antifungals,...

Full description

Saved in:
Bibliographic Details
Published in:International journal of rheumatic diseases 2023-01, Vol.26 (1), p.157-159
Main Authors: Mestre, Beatriz, Garcia, Jorge, Madruga Dias, João
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c4356-29a53d33ab038310553a3ebb08dbefdfc282b1451b5004b188a0eb80458abf1a3
cites cdi_FETCH-LOGICAL-c4356-29a53d33ab038310553a3ebb08dbefdfc282b1451b5004b188a0eb80458abf1a3
container_end_page 159
container_issue 1
container_start_page 157
container_title International journal of rheumatic diseases
container_volume 26
creator Mestre, Beatriz
Garcia, Jorge
Madruga Dias, João
description We report a rare case of long‐standing Hailey‐Hailey disease in a Caucasian Portuguese 69‐year‐old woman, recently diagnosed with rheumatoid arthritis. The patient's skin lesions remained active and exudative despite topical and oral treatments with corticosteroids, tetracyclines, antifungals, and oral treatment with azathioprine. After introduction of methotrexate for rheumatoid arthritis treatment, the skin lesions regressed, with significant impact on the patient's quality of life. This case report supports the clinical evidence of methotrexate's potential role in Hailey‐Hailey disease treatment.
doi_str_mv 10.1111/1756-185X.14456
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10092711</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2759925274</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4356-29a53d33ab038310553a3ebb08dbefdfc282b1451b5004b188a0eb80458abf1a3</originalsourceid><addsrcrecordid>eNqFkM1KAzEUhYMotlbX7mTAddvcZDI_KymiVikoouAuJDMZJ6Xt1CRj7c5H8Bl9EjNOLboym1xOTs49fAgdAx6AP0OIWdSHhD0NIAxZtIO6W2V3O4fQQQfWTjGOgEbxPurQiEBM4qiLbu5LVc-Fq3QeCONKo522gVjkwVjomVp_vn-0Q5Brq4RVgTNKOJUHK-3KYK5cWXnlzUuHaK8QM6uONncPPV5ePJyP-5Pbq-vz0aSfhdT3IalgNKdUSEwTCpgxKqiSEie5VEVeZCQhEkIGkmEcSkgSgZVMcMgSIQsQtIfO2txlLecqz9TCGTHjS6Pnwqx5JTT_-7LQJX-uXjlgnJIYwCecbhJM9VIr6_i0qs3Cl-YkZmlKGIlD7xq2rsxU1hpVbFcA5g193vDlDWv-Td__OPndbOv_we0NrDWsGqT_5fHR3aQN_gJi3ZFm</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2759925274</pqid></control><display><type>article</type><title>Rheumatoid arthritis and Hailey‐Hailey disease treated with methotrexate</title><source>Wiley-Blackwell Read &amp; Publish Collection</source><creator>Mestre, Beatriz ; Garcia, Jorge ; Madruga Dias, João</creator><creatorcontrib>Mestre, Beatriz ; Garcia, Jorge ; Madruga Dias, João</creatorcontrib><description>We report a rare case of long‐standing Hailey‐Hailey disease in a Caucasian Portuguese 69‐year‐old woman, recently diagnosed with rheumatoid arthritis. The patient's skin lesions remained active and exudative despite topical and oral treatments with corticosteroids, tetracyclines, antifungals, and oral treatment with azathioprine. After introduction of methotrexate for rheumatoid arthritis treatment, the skin lesions regressed, with significant impact on the patient's quality of life. This case report supports the clinical evidence of methotrexate's potential role in Hailey‐Hailey disease treatment.</description><identifier>ISSN: 1756-1841</identifier><identifier>EISSN: 1756-185X</identifier><identifier>DOI: 10.1111/1756-185X.14456</identifier><identifier>PMID: 36217276</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Aged ; Arthritis, Rheumatoid - diagnosis ; Arthritis, Rheumatoid - drug therapy ; Azathioprine ; Azathioprine - therapeutic use ; Case Report ; Case Reports ; Corticosteroids ; Female ; Hailey‐Hailey disease ; Humans ; Methotrexate ; Methotrexate - therapeutic use ; Patients ; Pemphigus, Benign Familial - diagnosis ; Pemphigus, Benign Familial - drug therapy ; Pemphigus, Benign Familial - pathology ; Quality of Life ; Rheumatoid arthritis ; Skin diseases ; Skin lesions ; Tetracyclines</subject><ispartof>International journal of rheumatic diseases, 2023-01, Vol.26 (1), p.157-159</ispartof><rights>2022 The Authors. published by Asia Pacific League of Associations for Rheumatology and John Wiley &amp; Sons Australia, Ltd.</rights><rights>2022 The Authors. International Journal of Rheumatic Diseases published by Asia Pacific League of Associations for Rheumatology and John Wiley &amp; Sons Australia, Ltd.</rights><rights>2022. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4356-29a53d33ab038310553a3ebb08dbefdfc282b1451b5004b188a0eb80458abf1a3</citedby><cites>FETCH-LOGICAL-c4356-29a53d33ab038310553a3ebb08dbefdfc282b1451b5004b188a0eb80458abf1a3</cites><orcidid>0000-0001-8956-8492 ; 0000-0002-9146-5318</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36217276$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mestre, Beatriz</creatorcontrib><creatorcontrib>Garcia, Jorge</creatorcontrib><creatorcontrib>Madruga Dias, João</creatorcontrib><title>Rheumatoid arthritis and Hailey‐Hailey disease treated with methotrexate</title><title>International journal of rheumatic diseases</title><addtitle>Int J Rheum Dis</addtitle><description>We report a rare case of long‐standing Hailey‐Hailey disease in a Caucasian Portuguese 69‐year‐old woman, recently diagnosed with rheumatoid arthritis. The patient's skin lesions remained active and exudative despite topical and oral treatments with corticosteroids, tetracyclines, antifungals, and oral treatment with azathioprine. After introduction of methotrexate for rheumatoid arthritis treatment, the skin lesions regressed, with significant impact on the patient's quality of life. This case report supports the clinical evidence of methotrexate's potential role in Hailey‐Hailey disease treatment.</description><subject>Aged</subject><subject>Arthritis, Rheumatoid - diagnosis</subject><subject>Arthritis, Rheumatoid - drug therapy</subject><subject>Azathioprine</subject><subject>Azathioprine - therapeutic use</subject><subject>Case Report</subject><subject>Case Reports</subject><subject>Corticosteroids</subject><subject>Female</subject><subject>Hailey‐Hailey disease</subject><subject>Humans</subject><subject>Methotrexate</subject><subject>Methotrexate - therapeutic use</subject><subject>Patients</subject><subject>Pemphigus, Benign Familial - diagnosis</subject><subject>Pemphigus, Benign Familial - drug therapy</subject><subject>Pemphigus, Benign Familial - pathology</subject><subject>Quality of Life</subject><subject>Rheumatoid arthritis</subject><subject>Skin diseases</subject><subject>Skin lesions</subject><subject>Tetracyclines</subject><issn>1756-1841</issn><issn>1756-185X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><recordid>eNqFkM1KAzEUhYMotlbX7mTAddvcZDI_KymiVikoouAuJDMZJ6Xt1CRj7c5H8Bl9EjNOLboym1xOTs49fAgdAx6AP0OIWdSHhD0NIAxZtIO6W2V3O4fQQQfWTjGOgEbxPurQiEBM4qiLbu5LVc-Fq3QeCONKo522gVjkwVjomVp_vn-0Q5Brq4RVgTNKOJUHK-3KYK5cWXnlzUuHaK8QM6uONncPPV5ePJyP-5Pbq-vz0aSfhdT3IalgNKdUSEwTCpgxKqiSEie5VEVeZCQhEkIGkmEcSkgSgZVMcMgSIQsQtIfO2txlLecqz9TCGTHjS6Pnwqx5JTT_-7LQJX-uXjlgnJIYwCecbhJM9VIr6_i0qs3Cl-YkZmlKGIlD7xq2rsxU1hpVbFcA5g193vDlDWv-Td__OPndbOv_we0NrDWsGqT_5fHR3aQN_gJi3ZFm</recordid><startdate>202301</startdate><enddate>202301</enddate><creator>Mestre, Beatriz</creator><creator>Garcia, Jorge</creator><creator>Madruga Dias, João</creator><general>Wiley Subscription Services, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T5</scope><scope>H94</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8956-8492</orcidid><orcidid>https://orcid.org/0000-0002-9146-5318</orcidid></search><sort><creationdate>202301</creationdate><title>Rheumatoid arthritis and Hailey‐Hailey disease treated with methotrexate</title><author>Mestre, Beatriz ; Garcia, Jorge ; Madruga Dias, João</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4356-29a53d33ab038310553a3ebb08dbefdfc282b1451b5004b188a0eb80458abf1a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Aged</topic><topic>Arthritis, Rheumatoid - diagnosis</topic><topic>Arthritis, Rheumatoid - drug therapy</topic><topic>Azathioprine</topic><topic>Azathioprine - therapeutic use</topic><topic>Case Report</topic><topic>Case Reports</topic><topic>Corticosteroids</topic><topic>Female</topic><topic>Hailey‐Hailey disease</topic><topic>Humans</topic><topic>Methotrexate</topic><topic>Methotrexate - therapeutic use</topic><topic>Patients</topic><topic>Pemphigus, Benign Familial - diagnosis</topic><topic>Pemphigus, Benign Familial - drug therapy</topic><topic>Pemphigus, Benign Familial - pathology</topic><topic>Quality of Life</topic><topic>Rheumatoid arthritis</topic><topic>Skin diseases</topic><topic>Skin lesions</topic><topic>Tetracyclines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mestre, Beatriz</creatorcontrib><creatorcontrib>Garcia, Jorge</creatorcontrib><creatorcontrib>Madruga Dias, João</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Wiley Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of rheumatic diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mestre, Beatriz</au><au>Garcia, Jorge</au><au>Madruga Dias, João</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rheumatoid arthritis and Hailey‐Hailey disease treated with methotrexate</atitle><jtitle>International journal of rheumatic diseases</jtitle><addtitle>Int J Rheum Dis</addtitle><date>2023-01</date><risdate>2023</risdate><volume>26</volume><issue>1</issue><spage>157</spage><epage>159</epage><pages>157-159</pages><issn>1756-1841</issn><eissn>1756-185X</eissn><abstract>We report a rare case of long‐standing Hailey‐Hailey disease in a Caucasian Portuguese 69‐year‐old woman, recently diagnosed with rheumatoid arthritis. The patient's skin lesions remained active and exudative despite topical and oral treatments with corticosteroids, tetracyclines, antifungals, and oral treatment with azathioprine. After introduction of methotrexate for rheumatoid arthritis treatment, the skin lesions regressed, with significant impact on the patient's quality of life. This case report supports the clinical evidence of methotrexate's potential role in Hailey‐Hailey disease treatment.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>36217276</pmid><doi>10.1111/1756-185X.14456</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0001-8956-8492</orcidid><orcidid>https://orcid.org/0000-0002-9146-5318</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1756-1841
ispartof International journal of rheumatic diseases, 2023-01, Vol.26 (1), p.157-159
issn 1756-1841
1756-185X
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10092711
source Wiley-Blackwell Read & Publish Collection
subjects Aged
Arthritis, Rheumatoid - diagnosis
Arthritis, Rheumatoid - drug therapy
Azathioprine
Azathioprine - therapeutic use
Case Report
Case Reports
Corticosteroids
Female
Hailey‐Hailey disease
Humans
Methotrexate
Methotrexate - therapeutic use
Patients
Pemphigus, Benign Familial - diagnosis
Pemphigus, Benign Familial - drug therapy
Pemphigus, Benign Familial - pathology
Quality of Life
Rheumatoid arthritis
Skin diseases
Skin lesions
Tetracyclines
title Rheumatoid arthritis and Hailey‐Hailey disease treated with methotrexate
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T01%3A53%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Rheumatoid%20arthritis%20and%20Hailey%E2%80%90Hailey%20disease%20treated%20with%20methotrexate&rft.jtitle=International%20journal%20of%20rheumatic%20diseases&rft.au=Mestre,%20Beatriz&rft.date=2023-01&rft.volume=26&rft.issue=1&rft.spage=157&rft.epage=159&rft.pages=157-159&rft.issn=1756-1841&rft.eissn=1756-185X&rft_id=info:doi/10.1111/1756-185X.14456&rft_dat=%3Cproquest_pubme%3E2759925274%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4356-29a53d33ab038310553a3ebb08dbefdfc282b1451b5004b188a0eb80458abf1a3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2759925274&rft_id=info:pmid/36217276&rfr_iscdi=true